Results 121 to 130 of about 3,964,387 (270)

FAST Drift Scan Survey for H i Intensity Mapping: Simulation of Bayesian-stacking-based H i Mass Function Estimation

The Astrophysical Journal
This study investigates the estimation of the neutral hydrogen (H i ) mass function (H i MF) using a Bayesian stacking approach with simulated data for the Five-hundred-meter Aperture Spherical radio Telescope (FAST) H i intensity mapping (H i IM) drift ...
Jiaxin Wang, Yichao Li, Hengxing Pan, Furen Deng, Diyang Liu, Wenxiu Yang, Wenkai Hu, Yougang Wang, Xin Zhang, Xuelei Chen   +9 more
doaj   +1 more source

Pyrrolyl Pyrazoles as Non-Diketo Acid Inhibitors of the HIV-1 Ribonuclease H Function of Reverse Transcriptase. [PDF]

ACS Med Chem Lett, 2020
Messore A, Corona A, Madia VN, Saccoliti F, Tudino V, De Leo A, Scipione L, De Vita D, Amendola G, Di Maro S, Novellino E, Cosconati S, Métifiot M, Andreola ML, Valenti P, Esposito F, Grandi N, Tramontano E, Costi R, Di Santo R.   +19 more
europepmc   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Generalized fractional integration of the \overline{H}-function

Le Matematiche, 2012
A significantly large number of earlier works on the subject of fractional calculus give interesting account of the theory and applications of fractional calculus operators in many different areas of mathematical analysis (such as ordinary and partial ...
Praveen Agarwal
doaj  

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

A basic analogue of Fox´s H-function

Revista Técnica de la Facultad de Ingeniería, 2011
Certain basic integrals and integral representations for a basic analogue of Fox´s H-function are investigated in this paper.
R. K. Saxena, G. C. Modi, S. L. Kalla
doaj  

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Fox’s H-Functions: A Gentle Introduction to Astrophysical Thermonuclear Functions

Axioms
Needed for cosmological and stellar nucleosynthesis, we are studying the closed-form analytic evaluation of thermonuclear reaction rates. In this context, we undertake a comprehensive analysis of three largely distinct velocity distributions, namely the ...
Hans J. Haubold, Dilip Kumar, Ashik A. Kabeer   +2 more
doaj   +1 more source