Results 121 to 130 of about 13,122,822 (311)

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

On some new bibliometric applications of statistics related to the h-index. [PDF]

open access: yes
In this note some new fields of application of Hirsch-related statistics are presented. Furthermore, so far unrevealed properties of the h-index are analysed in the context of rank-frequency and extreme-value statistics.
Glänzel, Wolfgang
core  

Journal Impact Factors for evaluating scientific performance : use of h-like indicators

open access: yes, 2010
This article introduces the Impact Factor squared or IF²-index, an h-like indicator of research performance. This indicator reflects the degree to which large entities such as countries and/or their states participate in top-level research in a field or ...
Boell, Sebastian K.   +7 more
core   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Design of Deep Learning-Based Pressure Injury Stage Classification Device

open access: yesJurnal Rekayasa Elektrika
Pressure injury or pressure ulcers could occur due to continuous pressure on the bony prominence of the skin and tissue. Geriatric patients, especially those with limited mobility and several comorbidities, are more susceptible to pressure injury.
Wahmisari Priharti   +4 more
doaj   +1 more source

Gender and the h-index in epidemiology

open access: yesScientometrics
AbstractGender-Based differences in h-indices across fields, including psychology, social work, and the biomedical sciences have been reported. These differences are persistent across all faculty ranks, including assistant, associate, and full professors, but may be larger for early career and senior faculty.
Jennifer Horney   +3 more
openaire   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

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