Results 91 to 100 of about 15,517,414 (328)

Ergothioneine supplementation improves pup phenotype and survival in a murine model of spinal muscular atrophy

open access: yesFEBS Letters, EarlyView.
Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile   +8 more
wiley   +1 more source

Microstructural evaluation of CoAl2O4 nanoparticles by Williamson–Hall and size–strain plot methods

open access: yesJournal of Asian Ceramic Societies, 2018
CoAl2O4 nanoparticles were prepared by a Pechini method using chelating agent citric acid. CoAl2O4 nanoparticles were synthesized at different calcination temperatures of 600–900°C.
H. Irfan, Mohamed Racik K., S. Anand
doaj   +1 more source

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

open access: yesMolecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka   +10 more
wiley   +1 more source

Frequency and association of disabled homolog 2-interacting protein (DAB2IP) variant rs7025486 G>A with coronary artery disease risk in Indian population

open access: yesIndian Heart Journal, 2018
Genome wide association study has identified rs7025486 G>A polymorphism within DAB2IP (Disabled homolog 2-interacting protein) gene with increased risk of coronary heart disease (CAD).
Aparna A. Bhanushali   +3 more
doaj  

The effects of cutting regimes on natural regeneration in submountain beech forests: species diversity and abundance

open access: yesJournal of Forest Science, 2008
The paper summarizes the results of 15-year natural regeneration for beech of five plots with different densities situated in the Western Carpathians Mts.
M. Barna
doaj   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

open access: yesMolecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

A new functional for charge and mass identification in Delta E-E telescopes

open access: yes, 2001
We propose a new functional for the charge and mass identification in Delta E-E telescopes. This functional is based on Bethe's formula, allowing safe interpolation or extrapolation in regions with low statistics.
Birks   +7 more
core   +3 more sources

Dalitz-plot analysis of the decays B±→K±π∓π±

open access: yes, 2005
We report a Dalitz-plot analysis of the charmless hadronic decays of charged B mesons to the final state K+/- pi-/+ pi+/-. Using a sample of 226.0 +/- 2.5 million BBbar pairs collected by the BaBar detector, we measure the magnitudes and phases of the ...
B. Aubert   +499 more
semanticscholar   +1 more source

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

open access: yesMolecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes   +20 more
wiley   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

open access: yesMolecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser   +11 more
wiley   +1 more source
mathematics
statistics
physics
biology
environmental science
computer science
medicine
plot graphics
chemistry
previous   8  9  10  11  12  

Home - About - Disclaimer - Privacy