Results 121 to 130 of about 15,517,414 (328)

SGLT2 inhibitors and the cardiac Na+/H+ exchanger-1: the plot thickens [PDF]

, 2021
Yu Jin Chung, Kyung Chan Park, Sergiy Tokar, Thomas R. Eykyn, William Fuller, Davor Pavlović, Pawel Swietach, Michael J. Shattock   +7 more
openalex   +1 more source

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

Molecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez, Pablo Juanes‐Velasco, Marina L. García‐Vaquero, Conrad Droste, Alicia Landeira‐Viñuela, Miguel Alcoceba, Helena Fidalgo‐Gómez, Sara Misiego‐Herrero, Almudena Navarro‐Bailón, Mónica Baile, José M. Bastida, Jose Manuel Sanchez‐Santos, Rafael Góngora, Julia Almeida, Marcos Gonzalez‐Diaz, Alberto Orfao, Javier De Las Rivas, Manuel Fuentes   +17 more
wiley   +1 more source

Halo-Independent Direct Detection Analyses Without Mass Assumptions

, 2015
Results from direct detection experiments are typically interpreted by employing an assumption about the dark matter velocity distribution, with results presented in the $m_\chi-\sigma_n$ plane.
Anderson, Adam J., Fox, Patrick J., Kahn, Yonatan, McCullough, Matthew   +3 more
core   +1 more source

Discussion: “Plotting Blower-Test Curves” (Anderson, A. H., 1917, Trans. ASME, 39, pp. 793–798) [PDF]

, 1917
J. M. Spitzglass, F. R. Still, Geo. F. Gebhardt, C. M. Spalding, Anthony Anderson   +4 more
openalex   +1 more source

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

Molecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova, Dominika Maurencova, Barbora Salovska, Marek Kratky, Tomas Mracek, Zuzana Korandova, Alena Pecinova, Pavla Vasicova, David Rysanek, Ladislav Andera, Ivo Fabrik, Rudolf Kupcik, Pavel Kashmel, Pinky Sultana, Vojtech Tambor, Jiri Bartek, Josef Novak, Marie Vajrychova, Zdenek Hodny   +18 more
wiley   +1 more source

Carbon Abundances in the Galactic Thin and Thick Disks

, 2005
Although carbon is, together with oxygen and nitrogen, one of the most important elements in the study of galactic chemical evolution its production sites are still poorly known and have been much debated (see e.g. Gustafsson et al. 1999; Chiappini et al.
Bensby, T., Feltzing, S.
core   +1 more source

Analysis of codon usage patterns in Hirudinaria manillensis reveals a preference for GC-ending codons caused by dominant selection constraints

BMC Genomics, 2018
Background Hirudinaria manillensis is an ephemeral, blood-sucking ectoparasite, possessing anticoagulant capacities with potential medical applications. Analysis of codon usage patterns would contribute to our understanding of the evolutionary mechanisms
De-Long Guan, Li-Bin Ma, Muhammad Salabat Khan, Xiu-Xiu Zhang, Sheng-Quan Xu, Juan-Ying Xie   +5 more
doaj   +1 more source

Early metastasis is characterized by Gr1+ cell dysregulation and is inhibited by immunomodulatory nanoparticles

Molecular Oncology, EarlyView.
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma, Sophia M. Orbach, Kate V. Griffin, Kathryn Kang, Yining Zhang, Rebecca S. Pereles, Ian A. Schrack, Guillermo Escalona, Jacqueline S. Jeruss, Lonnie D. Shea   +9 more
wiley   +1 more source

Crystallite Size Effect on Lattice Strain and Crystal Structure of Ba1/4Sr3/4MnO3 Layered Perovskite Manganite

, 2018
The single phase polycrystalline Ba1/4Sr3/4MnO3 layered perovskite manganite has been synthesized by combustion method having various crystallite sizes.
Kumar, Dinesh, Singh, Akhilesh Kumar, Singh, Monika   +2 more
core   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

Molecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu, Katherine Eason, Suet‐Feung Chin, Paul A. W. Edwards, Raquel Manzano Garcia, Richard Moulange, Jia Wern Pan, Soo Hwang Teo, Sach Mukherjee, Maurizio Callari, Carlos Caldas, Stephen‐John Sammut, Oscar M. Rueda   +12 more
wiley   +1 more source