Results 61 to 70 of about 11,881,819 (315)

Helicobacter pylori incidence and re-infection in the Aklavik H. pylori Project. [PDF]

open access: yes, 2013
Background. The Aklavik H. pylori Project (AHPP) (www.canhelpworkinggroup.ca) is a community-driven project examining Helicobacter pylori infection and its influence on health in a diverse Aboriginal community in the Northwest Territories.
Carraher, S.   +3 more
core   +1 more source

HADHA K406 Lactylation Regulates Metabolic Reprogramming and Suppresses Immune Responses in Gastric Cancer

open access: yesAdvanced Science, EarlyView.
HADHA K406 lactylation fuels fatty acid β‐oxidation and HMGCR‐dependent cholesterol biosynthesis, fostering immunosuppressive MDSCs and exhausted CD8+ T cells in gastric cancer. Loss of this modification blocks cholesterol production, remodels the tumor microenvironment, and tumor growth is suppressed via combined inhibition of HMGCR and LDHA ...
Maoxiao Feng   +10 more
wiley   +1 more source

Analyses of the association between Helicobacter pylori antibody titre and pathogenicity before and after eradication: results of the Kyushu and Okinawa population study, a retrospective observational cohort study

open access: yesBMJ Open
Objectives To assess the utility of Helicobacter pylori antibody testing, we evaluated the correlation between the H. pylori antibody titre and H. pylori-associated pathogenicity and the changes in antibody titre after H.
Norihiro Furusyo   +5 more
doaj   +1 more source

Helicobacter pylori cag-Pathogenicity island-dependent early immunological response triggers later precancerous gastric changes in Mongolian gerbils [PDF]

open access: yes, 2009
Infection with Helicobacter pylori, carrying a functional cag type IV secretion system (cag-T4SS) to inject the Cytotoxin associated antigen (CagA) into gastric cells, is associated with an increased risk for severe gastric diseases in humans.
Haas, Rainer   +13 more
core   +2 more sources

Survival Results by the Prospectively Determined Clinical Staging for Locally Advanced Gastric Cancer: A Follow‐Up Study of JCOG1302A

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
Prospectively determined clinical T and N categories clearly stratified long‐term survival in locally advanced gastric cancer. Patients with cT3N+, cT4aN0, cT4aN+, and cT4b disease showed unfavorable prognosis despite standard treatment. These findings may help optimize patient selection for perioperative treatment strategies.
Tsutomu Hayashi   +19 more
wiley   +1 more source

Helicobacter pylori infection and lactose intolerance increase expiratory hydrogen

open access: yesEXCLI Journal : Experimental and Clinical Sciences, 2022
Infection with Helicobacter pylori (H.pylori) may cause dyspepsia and/or unexplained functional nonspecific, gastrointestinal complaints of the irritable bowel syndrome (IBS) spectrum. Hitherto, in H.
Wolfgang J. Schnedl   +6 more
doaj   +1 more source

H pyloriEradication and GERD [PDF]

open access: yesCanadian Journal of Gastroenterology, 2001
ARTICLE SUMMARY Ninety-eight patients with healed duodenal ulcer (DU) and proven Helicobacter pylori gastritis were prospectively, randomly assigned to receive bismuth plus metronidazole plus amoxicillin; bismuth plus metronidazole plus placebo; or metronidazole plus two placebos, and were followed every three months for one year with a detailed ...
openaire   +3 more sources

Chromosomal Abnormalities, Drug Sensitivity and Resistance in Hematological Malignancies: A Comprehensive Overview by the Francophone Group of Hematological Cytogenetics (GFCH)

open access: yesAmerican Journal of Hematology, EarlyView.
ABSTRACT Chromosomal abnormalities have a major clinical impact on hematological malignancies, particularly with regard to treatment strategies. To preserve and consolidate fundamental knowledge in this rapidly evolving field, the Francophone Group of Hematological Cytogenetics (Groupe Francophone de Cytogénétique Hématologique, GFCH) conducted a ...
Florence Nguyen‐Khac   +16 more
wiley   +1 more source

A systematic review on drugs absorption modifications after eradication in Helicobacter pylori positive patients undergoing replacement therapy [PDF]

open access: yes, 2015
Background & Aims: Helicobacter pylori (H. pylori) infection has been suggested as a cause of impaired drug absorption. This infection leads to alteration of the gastric acid secretion that may change the conformational characteristics of drugs and their
Fiorini, G.   +10 more
core   +1 more source

An Adult Presentation of KIF11‐Related MCLID Syndrome: Case Report and 40‐Year Follow‐Up

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Pathogenic variants in KIF11 are linked to autosomal dominant syndromes with microcephaly, chorioretinopathy, lymphedema, and intellectual disability (MCLID), though adult presentations remain underreported. We report a 42‐year‐old female presenting with a de novo single‐amino acid in‐frame deletion in the KIF11 gene (c.1294_1296del; p ...
Thrishna Chathurvedula   +8 more
wiley   +1 more source

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