Results 211 to 220 of about 317,019 (228)

Degradomics for large‐scale mechanistic insights on proteases and proteolysis in human health

open access: yesThe FEBS Journal, EarlyView.
Proteolysis has an important role in human disease but remains relatively unexplored. Degradomics, the uncovering of proteolysis in tissues, cells, and proteins, uses mass spectrometry‐based terminomics to identify protein termini occurring therein (forward degradomics) and to define the actions of proteases (reverse degradomics).
Daniel R. Martin   +2 more
wiley   +1 more source

Spatially resolved mapping of histones reveals selective neuronal response in Rett syndrome

open access: yesThe FEBS Journal, EarlyView.
Loss of Mecp2 function is associated with Rett syndrome (RTT). MeCP2 regulates chromatin, yet its influence on histone composition and dynamics is unclear. Combining MALDI‐MSI with LCM–LC–MS/MS, we mapped histone proteoforms across the dentate gyrus, cornu ammonis, and cerebellum in two mouse models of RTT.
Frederike Schäfer   +6 more
wiley   +1 more source

Plasma Glycated and Oxidized Amino Acid-Based Screening Test for Clinical Early-Stage Osteoarthritis. [PDF]

open access: yesAntioxidants (Basel)
Al-Saei ANJM   +10 more
europepmc   +1 more source

The Role of Media in Regulatory Oversight: Evidence From Comment Letters

open access: yesFinancial Review, EarlyView.
ABSTRACT This study examines how media coverage impacts regulatory oversight of publicly listed firms. We find that Chinese firms with greater media attention, particularly those with negative media coverage, are more likely to receive increased regulatory oversight, as indicated by comment letters issued by stock exchanges.
Yizhe Dong   +3 more
wiley   +1 more source

Learning Styles, Engagement and Anxiety in AI‐Mediated Writing: A Multimodal Feedback Study

open access: yesInternational Journal of Applied Linguistics, EarlyView.
ABSTRACT Artificial intelligence (AI) tools now permeate English academic writing. However, evidence on how feedback modalities align with student differences and with psychological mechanisms remains limited. Prior work often reduced learning styles to simple matches with delivery modes and treated learning engagement and writing anxiety as peripheral.
Yi Ren   +3 more
wiley   +1 more source

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