Results 201 to 210 of about 47,138 (280)

Effects of the incorporation of honey from Apis mellifera from the Amazon savanna on the technological and sensory properties of yogurt during refrigerated storage. [PDF]

open access: yesPLoS One
do Rosário Silva MH   +11 more
europepmc   +1 more source

Structural Pharmacology of Estrogen-Related Receptors. [PDF]

open access: yesACS Pharmacol Transl Sci
Zhao P, Fang H, Elgendy B, Hegazy L.
europepmc   +1 more source

Allosteric Induction of Estrogen Receptor Ligand Binding Domain Tetramerization by a Distinct Complete Estrogen Receptor Antagonist. [PDF]

open access: yesACS Med Chem Lett
Fink EC   +9 more
europepmc   +1 more source

PPARγ Corepression Involves Alternate Ligand Conformation and Inflation of H12 Ensembles

open access: yesACS Chemical Biology, 2023
Inverse agonists of peroxisome proliferator activated receptor γ (PPARγ) have emerged as safer alternatives to full agonists for their reduced side effects while still maintaining impressive insulin-sensitizing properties. To shed light on their molecular mechanism, we characterized the interaction of the PPARγ ligand binding domain with SR10221. X-ray
Rebecca L. Frkic   +15 more
core   +6 more sources

An Overview of the H12 Performance Assessment in Perspective

open access: yesMRS Proceedings, 2002
ABSTRACTThe H12 performance assessment (PA) provided a test for the robustness of a HLW repository system concept based on structured siting and design, taking account of a wide range of potentially suitable Japanese geological environments. The generic nature of the host rock in the H12 assessment means, however, that emphasis is placed verymuch on ...
Kaname Miyahara   +8 more
openaire   +2 more sources

A stereoselective synthesis of (.+-.)-H12-histrionicotoxin and related photoaffinity-labeled congeners

Journal of the American Chemical Society, 1982
A practical six-step stereoselective total synthesis of (&)-perhydrohistrionicotoxin (4a) (H,,-HTX) is reported. The desired azaspir0(5S)undecane 6,6 ring system found in these alkaloid toxins has been constructed via the formic acid induced cyclization of either dihydropyridone 6 or carbinolamide 9. The photoaffinity-labeled toxin analogue 4c has also
David A. Evans   +2 more
exaly   +2 more sources

Application of Supplementary Safety Indicators for H12 Performance Assessment

open access: yesMRS Proceedings, 2000
ABSTRACTThe safety of a geological disposal system can be assessed using defined indicators such as risk and dose level, which directly measure radiological effects on human beings. Since the safety assessment of a geological disposal system covers a very long period of time, there are inherent uncertainties involved in assumptions about future human ...
A. Takasu, M. Naito, H. Umeki, S. Masuda
openaire   +2 more sources

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