Results 41 to 50 of about 42,199 (200)

The Natural Product Corramycin Acts as a DNA Gyrase Poison and Overcomes Fluoroquinolone Resistance in Mycobacterium tuberculosis

Advanced Science, EarlyView.
Corramycin, a myxobacterial natural product antibiotic, exhibits potent bactericidal activity against multidrug‐resistant Mycobacterium tuberculosis. The compound hijacks bacterial transporters such as BacA and OppABCD to enter the cell and inhibits DNA synthesis through a previously unrecognized mode of DNA gyrase poisoning, locking the enzyme in an ...
Franziska Fries, Jennifer Herrmann, Michael Dal Molin, Yaëlle Wormser, Timo Risch, Yunsheng Gao, Gareth Prosser, Francesca Gubellini, Ariel Mechaly, Joshua B. Wallach, Anthony Castro, Arka Banerjee, Sari Rasheed, Alexander Horn, Mathias Müsken, Michael Kurz, Lindsay Sonnenkalb, Viola Dreyer, Stefan Niemann, Sönke Andres, Dirk Schnappinger, Uli Kazmaier, Norbert Reiling, Rolf Müller, Jan Rybniker, Stéphanie Petrella   +25 more
wiley   +1 more source

Y-chromosome polymorphisms in 12 native, karagül, karacabey merino breeds from turkey and anatolian mouflon (ovis gmelinii anatolica) [PDF]

Kafkas Universitesi Veteriner Fakültesi Dergisi, 2018
In this study, 182 male animals from 12 native sheep breeds, as well as Karacabey Merino and Karagül breeds of Anatolia, wild sheep Anatolian Mouflon (Ovis gmelinii anatolica) were used as the study material.
Arif PARMAKSIZ, Ahmet OYMAK, Eren YÜNCÜ, Sevgin DEMİRCİ, Evren KOBAN BAŞTANLAR, Emel ÖZKAN ÜNAL, İnci TOGAN, Füsun ÖZER   +7 more
doaj   +1 more source

A new and robust method of tethering IgG surrogate antigens on lipid bilayer membranes to facilitate the TIRFM based live cell and single molecule imaging experiments. [PDF]

PLoS ONE, 2013
Our understanding of cell-cell interactions has been significantly improved in the past years with the help of Total Internal Reflection Fluorescence Microscope (TIRFM) in combination with an antigen presenting system supported by planar lipid bilayer ...
Shaosen Zhang, Liling Xu, Xingwang Zhao, Xin Chen, Yilin Fan, Zhengpeng Wan, Yinsheng Xu, Wanli Liu   +7 more
doaj   +1 more source

Humans and platyrrhines share a pattern of articular variance

The Anatomical Record, EarlyView.
Abstract Previous work has identified a pattern of articular shape variation in modern human limb joints, in which convex joint surfaces exhibit constrained variance relative to their more variable concave conarticulars. This pattern is notable given that joint morphogenesis is influenced by local biomechanical environments, which vary substantially ...
Haley Horbaly, Liam Zachary
wiley   +1 more source

Effective Performance of the 2022 American College of Rheumatology/EULAR Classification Criteria for Antineutrophil Cytoplasmic Antibody–Associated Vasculitis in Pediatric Patients: An ARChiVe Study

Arthritis &Rheumatology, EarlyView.
Objective To assess the 2022 American College of Rheumatology (ACR)/EULAR classification criteria for antineutrophil cytoplasmic antibody–associated vasculitis (AAV) in children with chronic small‐to‐medium vessel vasculitis. Methods A cohort of 574 patients, identified by physician's diagnosis (MD‐diagnosis) in A Registry of Childhood Vasculitis, was ...
David A. Cabral, Else S. Bosman, Nick McPhate, Simranpreet K. Mann, Kirandeep K. Toor, Kimberly A. Morishita, Raashid Luqmani, Michael W. Beresford, James Bistolarides, Sarah Campillo, Sirirat Charuvanij, Kathryn Cook, Paul Dancey, Marietta de Guzman, Samundeeswari Deepak, Barbara Eberhard, Melissa Elder, Samuel Gagne, Katie Harrison, Adam Huber, Archana Khan, Susan Kim, Marisa S. Klein‐Gitelman, Tzielan C. Lee, Suzanne C. Li, Neil Martin, Flora McErlane, L. Nandini Moorthy, Alvaro H. Orjuela, Jonathan Park, Phil Riley, Alan M. Rosenberg, Susan Shenoi, Vidya Sivaraman, Sodality Sutnga, Tamara Tanner, Stacey E. Tarvin, Marinka Twilt, Linda Wagner‐Weiner, Rae S. M. Yeung, Kelly L. Brown, for the ARChiVe Investigators Network within the PedVas Initiative   +41 more
wiley   +1 more source

Preclinical evaluation of rBCG-h12: an engineered Bacillus Calmette-Guérin with an enhanced activity against bladder and pancreatic cancers

Cancer Immunology, Immunotherapy
Background Intravesical Bacillus Calmette-Guérin (BCG) therapy has been the standard treatment for preventing recurrence of non-muscle-invasive bladder cancer (NMIBC) for over four decades.
Chang-Ching Yeh, Chi-Shuan Fan, Li-Li Chen, Kee Voon Chua, Chih-Hao Hsu, Chia-Chi Chen, Zhao-Lin Tan, Pei-Chu Tsai, Yung-Deng Song, Yong-Seng Low, Shiu-Ju Yang, Yih-Yuan Chen, Yi-Xiu Lin, Chia-Ming Wu, Horng-Yunn Dou, Tze-Sing Huang   +15 more
doaj   +1 more source

Estabelecimento, multiplicação e alongamento in vitro de Eucalyptus benthamii Maiden & Cambage x Eucalyptus dunnii Maiden Establishment, multiplication and elongation in vitro of Eucalyptus benthamii Maiden & Cambage x Eucalyptus dunnii Maiden

Revista Árvore, 2009
Neste trabalho foram testadas diferentes concentrações de cloro ativo (NaOCl) na assepsia de explantes para o estabelecimento in vitro, bem como benzilaminopurina (BAP) e ácido naftalenoacético (ANA) para a multiplicação e alongamento de Eucalyptus ...
Gilvano Ebling Brondani, Leonardo Ferreira Dutra, Fernando Grossi, Ivar Wendling, Jefferson Hornig   +4 more
doaj   +1 more source

Modeling Acoustic Attenuation, Sound Velocity and Wave Propagation in Lithium‐Ion Batteries via a Transfer Matrix

Batteries &Supercaps, Volume 8, Issue 3, March 2025.
“A simple 1D transfer matrix model of a battery is introduced and parametrized using harvested individual cell components at 0 % and 100 % SoC. This model allows for the calculation of group velocity and attenuation. The results of the model show good agreement with measured values, highlighting increased attenuation and group velocity at the ...
Simon Feiler, Lukas Gold, Sarah Hartmann, Guinevere A. Giffin   +3 more
wiley   +1 more source

Defossilisation of the Energy Supply of a Chemical Site by Integration of a Carnot Battery

Chemie Ingenieur Technik, EarlyView.
This study presents the results of a techno‐economic analysis of CO2‐free energy supply concepts for electricity and heat for the defossilisation of a chemical park in Germany for the model years 2030 and 2045. The focus is on the integration of a Carnot battery with thermal energy storage, which enables the flexible use of green fuels and renewable ...
Martin Bolten, Stefano Giuliano, Gerrit Koll, Judith Jäger, Arnulf Reitze, Michael Roling, Jana Stengler   +6 more
wiley   +1 more source

Designing Governance for ESG: Incentive and Oversight Complementarities in Corporate Sustainability Performance

Corporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT This study investigates how internal governance design supports credible ESG performance by distinguishing between Incentive and Oversight Architectures. Using 13,993 firm‐year observations of US nonfinancial firms from 2018 to 2024, we estimate fixed effects and two‐step system GMM models.
Beyza Gürel, Nehir Balci, Mustafa Reha Okur   +2 more
wiley   +1 more source