Results 1 to 10 of about 662 (128)

In silico modification of oseltamivir as neuraminidase inhibitor of influenza A virus subtype H1N1 [PDF]

Journal of Biomedical Research, 2015
This research focused on the modification of the functional groups of oseltamivir as neuraminidase inhibitor against influenza A virus subtype H1N1. Interactions of three of the best ligands were evaluated in the hydrated state using molecular dynamics simulation at two different temperatures. The docking result showed that AD3BF2D ligand (N-[(1S,6R)-5-
Usman Sumo Friend Tambunan, Arli Aditya Parikesit, Rizky Arcinthya Rachmania   +2 more
exaly   +3 more sources

Structural and Functional Analysis of NS1 and NS2 Proteins of H1N1 Subtype

Genomics, Proteomics and Bioinformatics, 2010
Abstract Influenza A virus (H1N1), a genetic reassortment of endemic strains of human, avian and swine flu, has crossed species barrier to human and apparently acquired the capability of human to human transmission. Some strains of H5N1 subtype are highly virulent because NS1 protein inhibits antiviral interferon α/β production.
Asad U Khan, Parveen Salahuddin
exaly   +3 more sources

Pulmonary Function and Clinical Manifestations of Patients Infected with Mild Influenza A Virus Subtype H1N1: A One-Year Follow-Up [PDF]

PLoS ONE, 2015
To investigate the long-term effects of mild H1N1 influenza infection on the pulmonary function of a cohort of patients.Forty-eight patients, all diagnosed with influenza A virus subtype H1N1 in 2009, were retrospectively included in this study.
Liping Peng, Shucheng Hua
exaly   +2 more sources

Identification of an H1N1 subtype of swine influenza virus and serological analysis

Journal of Integrative Agriculture, 2019
To investigate the epizootic of swine influenza virus (SIV), 60 nasal swabs were collected from a clinical cases of pig farm in Tai'an City, Shandong Province of China in April 2017. SIV was isolated by inoculating into 10-day-old Special Pathogen Free embryonated eggs and the whole genome was sequenced.
Yu-Chao Wang
exaly   +3 more sources

Meta-Analysis of Seroprevalence and Prevalence of Influenza A Viruses (Subtypes H3N2, H3N8, and H1N1) in Dogs

Animals
Influenza A is a zoonotic disease that affects dogs, pigs, horses, poultry, and birds. In this report, a meta-analysis according to PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) was conducted.
Ivan Ramos-Martínez, Edgar Ramos-Martínez, Manuel Saavedra-Montañez, Saraí Santos-Paniagua, René Segura-Velázquez, Onasis Vicente-Fermín, Mayte Martínez-Aguirre, Juan C. Ramos-Martínez, Sheila Irais Peña-Corona, Rodolfo Pastelin-Palacios, José Ivan Sánchez-Betancourt   +10 more
doaj   +3 more sources

Multiple reassortment events in the evolutionary history of H1N1 influenza A virus since 1918. [PDF]

PLoS Pathogens, 2008
The H1N1 subtype of influenza A virus has caused substantial morbidity and mortality in humans, first documented in the global pandemic of 1918 and continuing to the present day.
Martha I Nelson, Cécile Viboud, Lone Simonsen, Ryan T Bennett, Sara B Griesemer, Kirsten St George, Jill Taylor, David J Spiro, Naomi A Sengamalay, Elodie Ghedin, Jeffery K Taubenberger, Edward C Holmes   +11 more
doaj   +1 more source

High Prevalence of Influenza A (H1N1 and H3N2) Infection in South Iran [PDF]

Disease and Diagnosis, 2023
Background: Influenza A is divided into a number of subtypes, the most common of which are circulating H3N2 and H1N1. Influenza A and B viruses, which normally circulate in humans (human influenza viruses), are responsible for seasonal influenza ...
Khadijeh Ahmadi, Zahra Gharibi, Razieh Gorgi, Hamed Gouklani   +3 more
doaj   +1 more source

Successful management of fulminant influenza A subtype H1N1 myocarditis [PDF]

BMJ Case Reports, 2010
The outbreak and spread of the new influenza A subtype H1N1 reached pandemic levels during 2009, with greater numbers of cases reported daily and numerous complications described. The present report concerns an atypical manifestation of the disease in a previously healthy middle-aged patient who presented with severe, refractory cardiogenic shock 4 ...
Miguel, Cobas, Lilian, Abbo, Miguel, Santos, Clara, Baccini-Jauregui, Si, Pham   +4 more
openaire   +2 more sources

Human Properdin Released By Infiltrating Neutrophils Can Modulate Influenza A Virus Infection

Frontiers in Immunology, 2021
The complement system is designed to recognise and eliminate invading pathogens via activation of classical, alternative and lectin pathways. Human properdin stabilises the alternative pathway C3 convertase, resulting in an amplification loop that leads ...
Praveen M. Varghese, Praveen M. Varghese, Shuvechha Mukherjee, Futwan A. Al-Mohanna, Souad M. Saleh, Fahad N. Almajhdi, Nazar Beirag, Saad H. Alkahtani, Reena Rajkumari, Beatrice Nal Rogier, Robert B. Sim, Susan Idicula-Thomas, Taruna Madan, Valarmathy Murugaiah, Uday Kishore   +14 more
doaj   +1 more source

The Genomic Contributions of Avian H1N1 Influenza A Viruses to the Evolution of Mammalian Strains. [PDF]

PLoS ONE, 2015
Among the influenza A viruses (IAVs) in wild aquatic birds, only H1, H2, and H3 subtypes have caused epidemics in humans. H1N1 viruses of avian origin have also caused 3 of 5 pandemics.
Zeynep A Koçer, Robert Carter, Gang Wu, Jinghui Zhang, Robert G Webster   +4 more
doaj   +1 more source