Results 161 to 170 of about 94,535 (216)

Sustainability in Italian Dining: A Comparative Study of Perceptions in Full‐Service Restaurants and Agritourism

Business Strategy and the Environment, EarlyView.
ABSTRACT This study explores how sustainability is perceived and prioritized by consumers within full‐service restaurants and rural agritourism settings in Italy, examining the socio‐cultural and economic role of the HoReCa sector in promoting sustainable practices and analyzing gender and generational differences in consumer behavior.
Roberta Minazzi, Patrizia Gazzola, Daniele Grechi, Andrea Vitareti   +3 more
wiley   +1 more source

Powering Transparency: Global Drivers of Sustainability Reporting in the Electricity Sector

Business Strategy and the Environment, EarlyView.
ABSTRACT We examine the drivers of sustainability reporting quality (QSR), conceptualised along two complementary dimensions, relevance and reliability, to assess how firm‐level attributes and institutional conditions jointly shape disclosure practices in the electricity sector.
Alva Marasigan, Muhammad Nurul Houqe, Warwick Stent, Olayinka Moses   +3 more
wiley   +1 more source

Non imidazole H3-receptor histamine antagonists

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Histamine H3 Receptor Agonists

Mini-Reviews in Medicinal Chemistry, 2004
The SAR of H3 ligands has been difficult to evaluate because of species differences, multiple isoforms and constitutive activity, among other complicating factors. A review is given of the sometimes-conflicting affinity, activity and efficacy data of H3 agonists that has been described in literature to date.
I J P, De Esch, K J, Belzar
openaire   +3 more sources

H3 Receptor Miniseries: Histamine and H3 receptor in alcohol-related behaviors.

The Journal of Pharmacology and Experimental Therapeutics, 2020
Data from rat models for alcohol preference and histidine decarboxylase knockout (HDC KO) mice suggest that brain histamine regulates alcohol-related behaviors. Histamine levels are higher in alcohol-preferring than in alcohol-nonpreferring rat brains, and expression of histamine H(3) receptor (H(3)R) is different in key areas for addictive behavior. H(
Panula Pertti, Nuutinen Saara, Panula Pertti, Nuutinen Saara   +3 more
openaire   +3 more sources

Histamine H3-receptor isoforms

Inflammation Research, 2004
Increasing evidence supports a role for HA as a neurotransmitter and neuromodulator in various brain functions, including emotion, cognition, and feeding. The recent cloning of the histamine H3 receptor allowed for the subsequent cloning of a variety of H3 receptor isoforms from different species as well as the H4 receptor.
openaire   +2 more sources

Histamine homologues discriminating between two functional H3 receptor assays. Evidence for H3 receptor heterogeneity?.

The Journal of Pharmacology and Experimental Therapeutics, 1996
We studied several histamine homologues as potential ligands for the histamine H3 receptor in two binding assays ([125l]iodophenpropit and N alpha-[3H]methylhistamine binding to rat brain cortex membranes) and two functional H3 receptor models (inhibition of the neurogenic contraction in the guinea pig jejunum and of [3H]noradrenaline release in mouse ...
Leurs, R., Kathmann, M., Vollinga, R.C., Menge, W.M.P.B., Schlicker, E., Timmerman, H.   +5 more
openaire   +3 more sources

Novel Chiral H3-Receptor Agonists

1991
Several alkyl-substituted histamine derivatives have been synthesized and investigated for their agonistic potency on three classes of histamine receptors. While all investigated compounds are full agonists at H3-receptors their relative potency vs.
R, Lipp, J M, Arrang, J, Buschmann, M, Garbarg, P, Luger, W, Schunack, J C, Schwartz   +6 more
openaire   +2 more sources

Fluorinated non-imidazole histamine H3 receptor antagonists

Bioorganic & Medicinal Chemistry Letters, 2009
Fluorine substituents have become a widespread and important component in drug design and development. Here, the synthesis of fluorine containing compounds and some corresponding precursor molecules are presented for potential isotope labelling as well as their data obtained with in vitro and in vivo screenings. The compounds vary in the basic centres (
K, Isensee, M, Amon, A, Garlapati, A, Galaparti, X, Ligneau, J-C, Camelin, M, Capet, J-C, Schwartz, H, Stark   +8 more
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Non-imidazole heterocyclic histamine H3 receptor antagonists

Bioorganic & Medicinal Chemistry Letters, 2003
Continued exploration of the SAR around the lead imidazopyridine histamine H(3) antagonist 1 has led to the discovery of several related series of heterocyclic histamine H(3) antagonists. The synthesis and SAR of indolizine, indole and pyrazolopyridine based compounds are now described.
Wenying, Chai, J Guy, Breitenbucher, Annette, Kwok, Xiaobing, Li, Victoria, Wong, Nicholas I, Carruthers, Timothy W, Lovenberg, Curt, Mazur, Sandy J, Wilson, Frank U, Axe, Todd K, Jones   +10 more
openaire   +2 more sources