Results 181 to 190 of about 94,535 (216)

Novel H3 receptor antagonists. Sulfonamide homologs of histamine

Bioorganic & Medicinal Chemistry Letters, 1998
Sulfonamides derived from 4(5)-(omega-aminoalkyl)-1H-imidazoles containing chain lengths of three- to five-carbons were synthesized. Good to moderate H3 receptor binding affinities were observed for several butyl and pentyl homologs, whereas binding affinities were considerably weaker in the propyl series.
R, Wolin, M, Connolly, A, Afonso, J A, Hey, H, She, M A, Rivelli, S M, Willams, R E, West   +7 more
openaire   +2 more sources

H3 receptors in airways

Trends in Pharmacological Sciences, 1989
P J, Barnes, M, Ichinose
openaire   +2 more sources

Subclassification of histamine receports, H3-receptor subtypes? Localization of H3 receptors in the brain

1998
Publisher Summary Histamine is released in the brain from neurons projecting in a diffuse manner to widely divergent cerebral areas and arising from the tuberomammillary nucleus of the posterior hypothalamus. It affects target cells via the activation of three receptor subtypes that are termed H 1 , H 2 , and H 3 .
openaire   +1 more source

Histamine H3-Receptor Inverse Agonists as Novel Antipsychotics

Central Nervous System Agents in Medicinal Chemistry, 2009
Schizophrenia (SZ) that is resistant to treatment with dopamine (DA) D2 antagonists may involve changes other than those in the dopaminergic system. Recently, histamine (HA), which regulates arousal and cognitive functions, has been suggested to act as a neurotransmitter in the central nervous system.
openaire   +2 more sources

Systemic therapy for hormone receptor‐positive/human epidermal growth factor receptor 2‐negative early stage and metastatic breast cancer

Ca-A Cancer Journal for Clinicians, 2023
Laura A Huppert, Hope S Rugo
exaly  

Chimeric antigen receptor T‐cell therapy in multiple myeloma: A comprehensive review of current data and implications for clinical practice

Ca-A Cancer Journal for Clinicians, 2023
Rujul Parikh
exaly  

Critical care management of chimeric antigen receptor T‐cell therapy recipients

Ca-A Cancer Journal for Clinicians, 2022
Alexander Shimabukuro-Vornhagen, Victoria Metaxa, Elie Azoulay   +2 more
exaly  

Stress and brain H3-histamine receptors

Inflammation Research, 1995
P, Ghi, M, Blengio, C, Ferretti, P, Portaleone   +3 more
openaire   +2 more sources

H3 receptor gene is cloned at last

Trends in Pharmacological Sciences, 2000
R, Leurs, M, Hoffmann, K, Wieland, H, Timmerman   +3 more
openaire   +2 more sources

H3 Receptor Target: Past, Present, and Future Perspectives from Worldwide H3 Experts

2008
Divya Vohora, Andrew Medhurst, Nicholas Carruthers, Sylvain Celanire   +3 more
openaire   +1 more source