Results 11 to 20 of about 6,334 (187)

Cross-linking disulfide bonds govern solution structures of diabodies. [PDF]

Proteins, 2023
Abstract In the last years, antibodies have emerged as a promising new class of therapeutics, due to their combination of high specificity with long serum half‐life and low risk of side‐effects. Diabodies are a popular novel antibody format, consisting of two Fv domains connected with short linkers.
Math BA, Waibl F, Lamp LM, Fernández-Quintero ML, Liedl KR.   +4 more
europepmc   +2 more sources

Transcript and Lipid Profile Alterations in Astrocyte-Neuron Mitochondrial Transfer Under Lipopolysaccharide Exposure: An In Vitro Study. [PDF]

J Neurochem
The astrocyte‐conditioned medium (ACM) was obtained by incubating astrocytes with LPS (1 μg/mL) for 24 h. After removing cellular debris, the mitochondria‐depleted astrocyte‐conditioned medium (mdACM) was produced by filtering out mitochondria from ACM using a 0.2‐μm filter.
Kan Y, Wang H, Lin H, Li Y, Pei S, Cui Y, Xie K, Chen H, Yu Y.   +8 more
europepmc   +2 more sources

Using Fuzzy TOPSIS and Balanced Scorecard for Kaizen Evaluation

Business Systems Research, 2023
Kaizen is a very important continuous improvement technique; however, measuring kaizen results/benefits have not been clearly and comprehensively addressed by the literature.
El Dardery Ola I.S., Gomaa Ismail, Rayan Adel R. M., Frendy, Khayat Ghada El, Sabry Sara H.   +5 more
doaj   +1 more source

Transformation of the economic role of local self-government in low-urbanized territories in Ukraine: Initial conditions and social perception

International Journal of Management and Economics, 2022
Newly formed territorial communities acquire a real subjectivity in the processes of the management of territorial development: they become responsible for a significant share of day-to-day economic activities within their sphere of responsibility ...
Hlynskyy Nazar, Krykavskyy Yevhen, Hirna Olha, Savchenko Yuliia   +3 more
doaj   +1 more source

Improving Public Service Culture With Reduction of Interest Conflicts in State-Owned Enterprises (SOEs) Task Enforcement in Emerging Markets - Case In Vietnam

Management, 2020
Nowadays, many developing countries such as China, India and Vietnam, etc. have been trying to improve public service culture in public service organizations through eliminating corruption, more integrity, and training and improving good corporate ...
Hue Ly Thy
doaj   +1 more source

Inhibitor binding mode and allosteric regulation of Na+-glucose symporters. [PDF]

, 2018
Sodium-dependent glucose transporters (SGLTs) exploit sodium gradients to transport sugars across the plasma membrane. Due to their role in renal sugar reabsorption, SGLTs are targets for the treatment of type 2 diabetes.
Althoff, Thorsten, Bisignano, Paola, Friemann, Rosmarie, Ghezzi, Chiara, Grabe, Michael, Jacobson, Matthew P, Jo, Hyunil, Kalyanaraman, Chakrapani, Polizzi, Nicholas F, Wright, Ernest M   +9 more
core   +2 more sources

Ceftiofur use and antimicrobial stewardship in the horse

Equine Veterinary Journal, Volume 55, Issue 6, Page 944-961, November 2023., 2023
Abstract Equine practitioners require recommendations that support antimicrobial stewardship and avoid generating resistance to medically important antibiotics. This review examines current inadequacies in antimicrobial stewardship standards within the veterinary community, related to antimicrobial categorisation and prescribing practices.
Clare A. Ryan, Christina D. McNeal, Brenton C. Credille   +2 more
wiley   +1 more source

New accounting information system: An application for a basic social benefit in Spain

Revista de Contabilidad: Spanish Accounting Review, 2018
Accounting information on social benefits is included, in accordance with the scope of its management, in the general Social Security budget. The information contained in the budget may be relevant, but it is likely to be insufficient to enable ...
Noemí Peña-Miguel, Joseba Iñaki De La Peña   +1 more
doaj   +1 more source

Biochemical, kinetic, and spectroscopic characterization of Ruegeria pomeroyi DddW - A mononuclear iron-dependent DMSP lyase [PDF]

, 2015
The osmolyte dimethylsulfoniopropionate (DMSP) is a key nutrient in marine environments and its catabolism by bacteria through enzymes known as DMSP lyases generates dimethylsulfide (DMS), a gas of importance in climate regulation, the sulfur cycle, and ...
Brummett, Adam E, Crider, Alexander, Dey, Mishtu, Schnicker, Nicholas J, Todd, Jonathan   +4 more
core   +3 more sources

Dynamical changes of SARS‐CoV‐2 spike variants in the highly immunogenic regions impact the viral antibodies escaping

Proteins: Structure, Function, and Bioinformatics, Volume 91, Issue 8, Page 1116-1129, August 2023., 2023
Abstract The prolonged circulation of the SARS‐CoV‐2 virus resulted in the emergence of several viral variants, with different spreading features. Moreover, the increased number of recovered and/or vaccinated people introduced a selective pressure toward variants able to evade the immune system, developed against the former viral versions. This process
Lorenzo Di Rienzo, Mattia Miotto, Fausta Desantis, Greta Grassmann, Giancarlo Ruocco, Edoardo Milanetti   +5 more
wiley   +1 more source