Results 61 to 70 of about 342,809 (312)

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

H I Tidal Tails, Bridges and Clouds [PDF]

open access: yesSymposium - International Astronomical Union, 2004
There is plenty of intergalactic HI gas without any obvious stellar content ranging from (1) extended gas envelopes around some normal and peculiar galaxies, (2) tidal tails/bridges in interacting or merging galaxy systems, (3) large-scale rings around early type galaxies, and (4) detached clouds at varying distances from associated galaxies, but there
openaire   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

open access: yesFEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini   +2 more
wiley   +1 more source

Analysis of a Novel Four Level Flying Capacitor H – Bridge Converter

open access: yesInternational Journal of Renewable Energy Development, 2018
In this paper, a novel four-level flying capacitor inverter and its comparison with the conventional flying capacitor topology in terms of THD analysis are proposed.
Feyzullah Gülpınar   +2 more
doaj   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Asymmetric cascaded half-bridge multilevel inverter without polarity changer

open access: yesAlexandria Engineering Journal, 2018
In this paper, New asymmetric cascaded half H bridge multilevel inverter MLI is proposed. It is driven from the conventional asymmetric cascaded half H Bridge multilevel inverter.
Mahrous Ahmed   +2 more
doaj   +1 more source

H(2)-unknotting operation related to 2-bridge links

open access: yesTopology and its Applications, 2012
14 pages, 9 ...
openaire   +2 more sources

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

open access: yesFEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu   +5 more
wiley   +1 more source

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