Results 211 to 220 of about 20,346,263 (306)

Selective control of HLA-DRB1 and HLA-DQA1 transcription through DR/DQ super enhancer microelements. [PDF]

Cell Rep
Majumder P, Lee J, Butler R, Scharer CD, Boss JM.   +4 more
europepmc   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Convergent functional, white-matter microstructural, and cerebral perfusion abnormalities in overweight and obese adults: a multimodal MRI study. [PDF]

Front Nutr
Yin H, Yi Y, Yu Y, Liu L, Wu X, Huang R, Huang L, Qin W, Qin M, Yang W, Ding K.   +10 more
europepmc   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Nuclear speckle-associated perispeckle networks partition active chromatin into gene expression niches. [PDF]

Cell Rep
Chivukula Venkata N, Kim J, Misra S, Faber GP, Bektash A, Chaturvedi P, Hernandez Gonzalez GA, Dopie J, Kanemaki MT, Han KY, Shav-Tal Y, Belmont AS.   +11 more
europepmc   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

Solvent effects on the electronic structure, excited states, and nonlinear optical properties of two anthracene-based chalcone derivatives: a DFT and TD-DFT study. [PDF]

J Mol Model
Medeiros R.
europepmc   +1 more source

The Extent of H II Regions.

The Astrophysical Journal, 1960
openaire   +1 more source