Results 101 to 110 of about 262,778 (317)

Mechanisms of Aristolochic Acid Resistance in Specialist Butterflies and Evolutionary Insights for Potential Protective Pathways

open access: yesAdvanced Science, EarlyView.
The study provides an extreme example of insect adaptation to highly toxic defenses of host plants, and investigates the complex strategies to resist carcinogenic aristolochic acids, including physical isolation, metabolic detoxification, and DNA repair.
Yang Luan   +20 more
wiley   +1 more source

Programmable Pentamolecular Cross‐Scale Imaging Reveals the Multiplicative Synergistic Effect of High‐Fat / High‐Salt Diet on Atherosclerosis

open access: yesAdvanced Science, EarlyView.
This study demonstrates multifactorial lifestyle impacts on the pathogenesis and progression of cardiovascular diseases by a nanofluorescence sensor array for detecting four redox species and protein phosphorylation levels. Through cross‐scale fluorescence imaging of rats with different diets, we revealed that compared with single dietary interventions,
Jin Li   +9 more
wiley   +1 more source

Orientation‐Dependent Phase Transformation Pathways Enabling Superior Superelastic and Elastocaloric Performance of NiTi Alloys

open access: yesAdvanced Science, EarlyView.
By integrating simulations and experiments, the preferred (001) crystallographic texture promotes reversible martensite formation through variant selection, enhancing both superelastic and elastocaloric performance. This work provides fundamental guidelines for designing high‐efficiency NiTi‐based functional materials. Abstract Developing elastocaloric
Jiaqi Lu   +5 more
wiley   +1 more source

The Influence of Eating Habits on Type 2 Diabetes in Saudi Arabia: A Systematic Review [PDF]

open access: diamond, 2023
Osama O. Almutairi   +5 more
openalex   +1 more source

Microglial GPR35 Ameliorates Epileptogenesis and Neuroinflammation via PDGFA Domain 2 Signaling

open access: yesAdvanced Science, EarlyView.
Activation of microglial G protein–coupled receptor 35 (GPR35) by L‐kynurenic acid (L‐Kyna) initiates a platelet‐derived growth factor A (PDGFA)–dependent phosphoinositide 3‐kinase–protein kinase B (PI3K–AKT) signaling cascade that dampens hippocampal neuroinflammation, thereby restraining epileptogenesis, lowering seizure susceptibility, and ...
Qi Wang   +17 more
wiley   +1 more source

Colorectal Cancer Cell's Weapon: RNF32 Engages SPP1+ Macrophages to Foster Liver Metastasis, Targeted by Indole‐3‐Acetic Acid

open access: yesAdvanced Science, EarlyView.
Cytoplasmic RNF32 fuels CRC liver metastasis by degrading GSK3β, which stabilizes β‐catenin and activates Wnt/EMT. Moreover, RNF32 rewires the metastatic niche: it depletes CD8+/CD4+ T and NK cells while recruiting SPP1+ macrophages (which boost tumor stemness via CD44), fibroblasts, and immunosuppressive monocytes to aid colonization.
Hongyu Wang   +12 more
wiley   +1 more source

Molecular Weaving of Mixed‐Addenda Polyoxometalates into MOF Nanochannels as Electron‐Buffering Reservoirs for Enhanced Nitrate‐to‐Ammonia Electrocatalysis

open access: yesAdvanced Science, EarlyView.
Synergistic interaction between P2W17V1 and FeMOF owing to its efficient proton/electron transfer affording high yield and Faradaic efficiency in electrocatalytic nitrate reduction to ammonia. ABSTRACT Electrochemical conversion of nitrate pollutants into value‐added ammonia (e‐NO3RA) offers a sustainable pathway for nitrogen valorization, yet hinges ...
Gang Li   +3 more
wiley   +1 more source

Intrinsic Negative Magnetoresistance and Broadband Photoresponse in Magnetic van der Waals Crystal TaFeTe2

open access: yesAdvanced Science, EarlyView.
2D van der Waals (vdW) materials MM′Te2 with broken symmetry attract great interest for unique magnetic structures and optical‐phonon‐induced phase transitions. We report mechanically exfoliable TaFeTe2 single crystals, exhibiting spin‐glass behavior, intrinsic unsaturated negative magnetoresistance up to 9 T, self‐powered internal photocurrent, and ...
Changcun Li   +7 more
wiley   +1 more source

The Persistence of Habit: Tantric Engagements with Dharmakīrti’s View of Yogic Perception

open access: yesJournal of Contemplative Studies
Dharmakīrti’s view of yogic perception (yogipratyakṣa) and mental cultivation (bhāvanā) has generated a good deal of discussion—in Dharmakīrti’s text tradition, in the works of its various critics, and in the contemporary study of Buddhist philosophy ...
Davey K. Tomlinson
doaj   +1 more source

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