Results 111 to 120 of about 1,449,422 (393)

NAD+‐Boosters Improve Mitochondria Quality Control In Parkinson's Disease Models Via Mitochondrial UPR

open access: yesAdvanced Science, EarlyView.
Treatment of MPTP‐incubated cells with NAD+‐boosters increase the UPRmt/mitophagy‐related mitochondria quality control (MQC). Disturbed plasma UPRmt‐mitophagy‐mediated MQC profiles in PD patient samples. NMN inhibits motor deficit and forestalls neuropathology phenotypes of PD mice, which is required the atf4‐medicated UPRmt pathway.
Shuoting Zhou   +16 more
wiley   +1 more source

Szkaplerz – Ikonografia przedstawień

open access: yesArchiwa, Biblioteki i Muzea Kościelne, 2016
Powstanie małego szkaplerza było wynikiem zrzeszania się wiernych w bractwa i tercjarstwa. Dzięki temu osoby świeckie mogły na co dzień nosić szkaplerz jako zewnętrzny znak nawiązujący do ubrania zakonnego, który stał się symbolem okrycia szatą ...
Jolanta Wasilewska
doaj   +1 more source

Preference Heterogeneity and Habit Persistence: The Case of Breakfast Cereal Consumption [PDF]

open access: yes
This paper estimates the strength and heterogeneity across households in state dependence associated with breakfast cereal consumption, where positive state dependence implies habit persistence and negative state dependence implies variety-seeking in ...
Thunström, Linda
core   +1 more source

A Habit of Cattle [PDF]

open access: yesNature, 1879
MR. H. C. DONOVAN, in a letter headed as above (NATURE, vol. xx. p. 457), describes the bone munching of cattle in Natal, and asks whether they have a similar habit in other places. Such is the case in Norway, especially at the upper pasturages around the “saeters,” or mountain chalets, where they are commonly supplied with a daily modicum of fish ...
openaire   +2 more sources

Brain‐Wide Spatiotemporally Distinct Traveling Waves Drive Anxiety‐Like Behaviors in Mice

open access: yesAdvanced Science, EarlyView.
J.Liu et al. reveal the complete propagation dynamics of cortical traveling waves, from local circuitry initiation to long‐range propagation, and identify their functional relevance in modulating anxiety‐like behaviors and underlying cellular neuroplasticity in mice.
Jiaming Liu   +15 more
wiley   +1 more source

Alnustone Ameliorates Metabolic Dysfunction‐Associated Steatotic Liver Disease by Facilitating Mitochondrial Fatty Acid β‐Oxidation via Targeting Calmodulin

open access: yesAdvanced Science, EarlyView.
This study identifies alnustone, a natural compound from Alpinia katsumadai, as a potent therapeutic agent for MASLD and MASH. Alnustone enhances mitochondrial fatty acid β‐oxidation by directly targeting calmodulin, improving liver steatosis, fibrosis, and insulin resistance in vivo.
Shourui Hu   +13 more
wiley   +1 more source

Nicotine Reprograms Aging‐Related Metabolism and Protects Against Motor Decline in Mice

open access: yesAdvanced Science, EarlyView.
Long‐term oral nicotine intake protects against age‐related motor decline in mice without eliciting systemic toxicity. Integrated multi‐organ metabolomic profiling and longitudinal gut microbiota analyses reveal that nicotine induces coordinated remodeling of glycolipid and sphingolipid metabolism, enhances NAD⁺ bioavailability, and suppresses ceramide
Shuhui Jia   +29 more
wiley   +1 more source

Land of Addicts? An Empirical Investigation of Habit-Based Asset Pricing Behavior [PDF]

open access: yes
This paper studies the ability of a general class of habit-based asset pricing models to match the conditional moment restrictions implied by asset pricing theory.
Sydney C. Ludvigson, Xiaohong Chen
core  

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