Results 221 to 230 of about 272,492 (313)

Leptin May Promote Eosinophilic CRSwNP Progression by Enhancing Eosinophil Chemotaxis and Angiogenesis Under a Type 2 Inflammatory Milieu

open access: yesInternational Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Chronic rhinosinusitis with nasal polyp (CRSwNP) is a heterogeneous Type 2 inflammatory disease characterized by enhanced eosinophilic infiltration. Both innate and adaptive immunity are involved in the onset and progression of CRSwNP.
Yuki Sonoda   +4 more
wiley   +1 more source

Chronic alcohol consumption compromises gut barrier integrity and promotes endotoxemia: Implications for sepsis susceptibility in immunocompromised hosts

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Chronic alcohol exposure disrupts intestinal barrier integrity, resulting in a leaky gut and enhanced translocation of lipopolysaccharide (LPS) and microbial products into the systemic circulation. Alcohol‐induced endotoxemia drives exaggerated pro‐inflammatory responses, mitochondrial damage, and activation of the cGAS–STING pathway, particularly in ...
Thansita Bhunyakarnjanarat   +5 more
wiley   +1 more source

AI‐Driven Mapping of Seizure Spread Patterns

open access: yesAnnals of Neurology, EarlyView.
Objective The focus of epilepsy research has largely been on seizure onset; however, physicians typically examine the patterns of seizure spread past seizure onset as well. This study aims to align automated seizure analysis with clinical practice, leverage deep learning to standardize seizure annotations that varies among physicians, and understand ...
Andrew Y. Revell   +13 more
wiley   +1 more source

Additives Enhancing Biodegradability in Plastics and Potential Implications for Textiles: A Mechanistic Review

open access: yesJournal of Applied Polymer Science, EarlyView.
Mechanistic insights from additive‐assisted plastic degradation guide the design of environmentally adaptive textile fibers. Functional additives enhance oxidative, hydrolytic, enzymatic, and microbial degradation pathways. Translating these strategies requires control of fiber architecture, additive distribution, and environmental interactions ...
Julia Cunniffe   +2 more
wiley   +1 more source

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