Results 111 to 120 of about 1,259,407 (401)

What Should We Do About Habitual Caffeine Use in Athletes?

Sports Medicine, 2018
Caffeine is a well-established ergogenic aid, demonstrated to enhance performance across a wide range of capacities through a variety of mechanisms. As such, it is frequently used by both athletes and non-athletes alike.
C. Pickering, J. Kiely
semanticscholar   +1 more source

Tumor‐agnostic detection of circulating tumor DNA in patients with advanced pancreatic cancer using targeted DNA methylation sequencing and cell‐free DNA fragmentomics

Molecular Oncology, EarlyView.
We evaluated circulating tumor DNA (ctDNA) detection in advanced pancreatic cancer using DNA methylation, cell‐free DNA fragment lengths, and 5′ end motifs. Machine learning models were trained to estimate ctDNA levels from each feature and their combination.
Morten Lapin, Kjersti Tjensvoll, Karin Hestnes Edland, Satu Oltedal, Herish Garresori, Bjørnar Gilje, Saga Ekedal, Trygve Eftestøl, Jan Terje Kvaløy, Filip Janku, Oddmund Nordgård   +10 more
wiley   +1 more source

METABOLOMICS IN THE IDENTIFICATION OF BIOMARKERS OF DIETARY INTAKE

Computational and Structural Biotechnology Journal, 2013
Traditional methods for assessing dietary exposure can be unreliable, with under reporting one of the main problems. In an attempt to overcome such problems there is increasing interest in identifying biomarkers of dietary intake to provide a more ...
Aoife O'Gorman, Helena Gibbons, Lorraine Brennan   +2 more
doaj   +3 more sources

Habitual coffee consumption and cognitive function: a Mendelian randomization meta-analysis in up to 415,530 participants

Scientific Reports, 2018
Coffee’s long-term effect on cognitive function remains unclear with studies suggesting both benefits and adverse effects. We used Mendelian randomization to investigate the causal relationship between habitual coffee consumption and cognitive function ...
Ang Zhou, Amy E Taylor, V. Karhunen, Y. Zhan, S. Rovio, J. Lahti, P. Sjögren, L. Byberg, D. Lyall, J. Auvinen, T. Lehtimäki, M. Kähönen, N. Hutri-Kähönen, M. Perälä, K. Michaëlsson, A. Mahajan, L. Lind, C. Power, J. Eriksson, O. Raitakari, S. Hägg, N. Pedersen, J. Veijola, M. Järvelin, M. Munafo, E. Ingelsson, D. Llewellyn, E. Hyppönen   +27 more
semanticscholar   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

Molecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard, Cristina Mitric, Melanie Care, Tracy L. Stockley, Raymond H. Kim, Jeanna McCuaig, Blaise Clarke, Laura Ranich, Clare Sheen, Sarah E. Ferguson, Liat Hogen, Taymaa May, Marcus Q. Bernardini   +12 more
wiley   +1 more source

LEXAMBIENTE Rivista Trimestrale di Diritto Penale dell’Ambiente Fasc. n. 4/2019 38 Il reato di trasporto di rifiuti (art. 256, 1° comma, d.lgs. 152/06): istantaneità vs permanenza The crime of transportation of waste (art. 256, 1st paragraph, d.lgs. 152/06): instantaneousness vs permanence

Lexambiente, 2019
The paper criticizes the Court of Cassation which qualifies the case of the illegal transport of waste (art. 256, 1st paragraph, Legislative Decree 152/06) as an instantaneous or, at the most, possibly habitual offense and instead affirms its nature ...
Vincenzo Paone
doaj  

The reflective learning continuum: reflecting on reflection [PDF]

, 2005
The importance of reflection to marketing educators is increasingly recognized. However, there is a lack of empirical research which considers reflection within the context of both the marketing and general business education literature.
Amanda Hay, Argyris, C., Bennis, W., Biggs, J., Bloom, B. S., Boud, D., Boud, D., Braun, N. M., Densten, I. L., Dewey, J., Entwhistle, N., James W. Peltier, Kolb, D. A., Kouzes, J. M., Loo, R., Marton, F., Mezirow, J., Mintzberg, H., Mintzberg, H., Mukherjee, A., Nunnally, J., Porter, L., Schön, D. A., Schön, D. A., Stevens, G. E., Taylor, E., William Drago, Willmott, H.   +27 more
core   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

From LIKE/LOVE to habitual: the case of Mainland East and Southeast Asian languages

Linguistics
This paper documents the common grammaticalization path of the LIKE/LOVE constructions into expressing habitual aspect in Mainland East and Southeast Asian languages. The stages and degrees of grammaticalization for the LIKE/LOVE constructions vary cross-
Fang Hongmei
doaj   +1 more source