Results 211 to 220 of about 103,097 (278)

Exploring spillover effects beyond workplace dietary interventions using agent-based modelling. [PDF]

Public Health Nutr
Zhu Y, Ocké M, de Vet E.
europepmc   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Glycine Reverses Behavioral Deficits in a Mouse Model for Psychosis With 4 Copies of the Gldc Gene. [PDF]

Pharmacol Res Perspect
Wang M, Kambali M, Lyu J, Nagarajan R, Rudolph U.   +4 more
europepmc   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Assessing Executive Cognitive Functions in Sheep: A Scoping Review of Recent Literature on Cognitive Tasks. [PDF]

Animals (Basel)
Galanti D, Dalla Costa E, Barbieri S, Minero M.   +3 more
europepmc   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Conspecific Presence Promotes Social Buffering, Restores Social Reward, and Enhances Spatial Navigation in a Ketamine-Induced Model of Schizophrenia in Mice. [PDF]

Eur J Neurosci
Monteiro RFM, Nascimento MVL, Lima KT, Cardoso VSL, Almeida JRG, Costa WJTN, Teixeira BEG, Shirakura VT, Souza SA, Cassoli JS, de Nazareth Tavares Bastos G.   +10 more
europepmc   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Evaluating Aversion to Eye-Like Stimuli as a Foraging Deterrent in Urban European Herring Gulls. [PDF]

Ecol Evol
Kelley LA, Hunter Thompson R, Rowe B, Boogert NJ.   +3 more
europepmc   +1 more source

Neurobehavioral Assessment of Sensorimotor Function in Autism Using Smartphone Technology. [PDF]

Autism Res
Gultig KD, Boele CP, Roggeveen LEM, Soong TF, Sherry S, Jung C, Milosevska S, Uvarov A, Benhassan K, BenAli SA, Ahajoui Y, Carpio-Arias V, Lindeman S, Koekkoek SKE, Sefik E, Ottenhoff MJ, Wang SS, De Zeeuw CI, El Idrissi A, Boele HJ.   +19 more
europepmc   +1 more source