Results 61 to 70 of about 182,378 (305)

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski, Rebecca Ronsley, Shannon M. Stasi, Jeffrey Stevens, Erin R. Rudzinski, Christina M. Lockwood, Sarah E. S. Leary, Bonnie L. Cole, Michelle A. Ting, Vera Paulson   +9 more
wiley   +1 more source

Kepemimpinan Kepala Madrasah Ibtidaiyah dalam Implementasi Permendikbud Nomor 23 Tahun 2015

INSANIA: Jurnal Pemikiran Alternatif Kependidikan, 2021
This study aims to describe the leadership practices of the head of MI Ma'arif NU Kedungwringin Banyumas in the implementation of Permendikbud Number 23 of 2015. The study was conducted using qualitative approach with a phenomenological research.
Siswadi Siswadi
doaj   +1 more source

A Bio-Logical Theory of Animal Learning [PDF]

, 2009
This article provides the foundation for a new predictive theory of animal learning that is based upon a simple logical model. The knowledge of experimental subjects at a given time is described using logical equations.
A Blaisdell, A Wagner, C Brimer, C Gallistel, D Hebb, David Guez, G Boole, I Pavlov, J Pearce, J Pearce, J Uexküll Von, K Lattal, LJ Kamin, M Goddard, M Haselgrove, M Karnaugh, N Mackintosh, R Atkinson, R Guez, R Miller, R Miller, R Rescorla, R Rescorla, R Rescorla, R Rescorla, R Rescorla, R Rescorla, R Rescorla, R Rescorla, T Beckers, T Bliss, T Bliss, T Higgins   +32 more
core   +2 more sources

Outcomes of Live Virus Vaccination in Patients With Vascular Anomalies Being Treated With Sirolimus

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Live vaccination in patients with vascular anomalies (VA) receiving sirolimus remains controversial due to immunosuppressive effects and theoretical risks. Procedure This single‐center retrospective study included patients with VA less than 4 years old at the start of sirolimus therapy who were incompletely vaccinated.
Svatava Merkle, Kiersten Ricci, Kelly Blache, Rebecca A. Marsh, Adrienne M. Hammill, Elissa Engel   +5 more
wiley   +1 more source

Understanding inter-individual variability of experimental pain habituation and conditioned pain modulation in healthy individuals

Scientific Reports
Although reduced experimental pain habituation is proposed as a proxy of diminished endogenous pain modulatory capacity in chronic pain, prior studies show contradictory findings.
Iara De Schoenmacker, Paulina S. Scheuren, Laura Sirucek, Robin Lütolf, Lindsay M. Gorrell, Jan Rosner, Armin Curt, Petra Schweinhardt, Michèle Hubli   +8 more
doaj   +1 more source

Pulmonary Dysfunction Is Associated With Sleep Study Abnormalities in Children With Sickle Cell Disease: A Multicenter Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Pulmonary dysfunction and sleep abnormalities are common in children with sickle cell disease (SCD) and are associated with worse clinical outcomes. Whether spirometry abnormalities are associated with polysomnography (PSG) findings remains unclear.
Ammar Saadoon Alishlash, Anis Rabbani Nourani, A. K. M. Fazlur Rahman, Dima Ezmigna, Tarig Ali‐Dinar   +4 more
wiley   +1 more source

Prevalence and Trajectory of Household Material Hardship Among Children With Advanced Cancer

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background/Objectives Families of children with advanced cancer living in poverty experience inferior outcomes including poor parent mental health and worse child quality of life. Household material hardship (HMH: food, housing, transportation, and/or utility insecurity) is a modifiable poverty exposure—and potential intervention target—that ...
Sarah Wright, Morgan A. Paul, Selena Murcia Mendez, Emily Jones, Lucille Lokko, Chelsea Heneghan, Nicholas Purol, Morgan Arnold, Rahela Aziz‐Bose, Colleen A. Kelly, Sandi L. Pruitt, Joanne Wolfe, Kira Bona, Puja J. Umaretiya   +13 more
wiley   +1 more source

Germline TP53 Mutations Causing Diamond–Blackfan Anemia: A French Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Diamond–Blackfan anemia is a rare congenital erythroblastopenia typically caused by mutations in ribosomal protein genes. Recently, gain‐of‐function mutations in TP53 have been identified as a novel cause of Diamond–Blackfan anemia. We report two French patients who both harbored a heterozygous TP53 deletion (NM_000546.5: c.1077delA; p ...
Rafael Moisan, Lydie Da Costa, Ludivine David Nguyen, Heloise Chosseler, Audrey Riquet, Benedicte Bruno, Melissa Barbati   +6 more
wiley   +1 more source

Ethanol alters mechanosensory habituation in C. elegans by way of the BK potassium channel through a novel mechanism.

PLoS ONE
In this research, we investigated how alcohol modulates the simplest form of learning, habituation, in Caenorhabditis elegans. We used our high throughput Multi-Worm Tracker to conduct a large scale study of more than 21,000 wild-type worms to assess the
Nikolas Kokan, Conny Lin, Alvaro Luna, Joani Viliunas, Catharine H Rankin   +4 more
doaj   +1 more source

Naturalization: Habits, Bodies and Their Subjects

Phenomenology and Mind, 2016
The paper seeks to draw a preliminary map of the relations between the human body, habituation, and nature, in a lineage of questioning which should be referred to as Aristotelian in the wider sense of the term.
Adi Efal
doaj   +1 more source