Results 111 to 120 of about 259,069 (300)
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Every word starts with a 'dis': the impact of class on choice, application and admissions to prestigious higher education art and design courses [PDF]
, 2006 The UK government's commitment to increasing the number of working class students in higher education places little emphasis on who goes to which university to study what subject.
McManus, Jackie
core
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
A new North American species of Microrhagus Dejean, 1833 (Coleoptera: Eucnemidae) : with a key to the Nearctic species [PDF]
, 2013 Microrhagus brunneus, new species (Coleoptera: Eucnemidae: Melasinae: Dirhagini) is described from Arkansas, Indiana, Kentucky, Louisiana, North Carolina, Oklahoma and Wisconsin.
Otto, Robert L.
core
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Hibriditas Musik Dangdut dalam Masyarakat Urban
Journal of Urban Society's Arts, 2014 Dangdut, merupakan jenis musik yang mengalami dan menemani perubahanyang terjadi di Indonesia. Eksistensinya menandakan dangdut merupakan jenismusik yang paling bertahan selama beberapa dekade.
Michael H.B. Raditya
doaj
A review of described Metacyrba, the status of Parkella, and notes on Platycryptus and Balmaceda : with a comparison of the genera (Araneae: Salticidae: Marpissinae) [PDF]
, 2005 Parkella Chickering 1946 = Metacyrba F. O. P.-Cambridge 1901, n. syn.; Parkella venusta Chickering 1946 = Metacyrba venusta (Chickering 1946), n. comb.; Parkella fusca Chickering 1946 and Dendryphantes franganilloi Caporiacco 1955 = Metacyrba venusta ...
Edwards, G. B.
core
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Sociologia: Revista da Faculdade de Letras da Universidade do Porto, 2004 Departing from the work of Pierre Bourdieu, the present paper outlines the genesis of the notion of habitus and provides an overview of some of its key theoretical properties.
Loïc Wacquant
doaj