Five‐Year Disease Progression in Synuclein Seeding Positive Sporadic Parkinson's Disease
ABSTRACT Objective To provide a comprehensive description of disease progression in synuclein seeding assay (SAA) positive sporadic Parkinson Disease participants, using Neuronal Synuclein Disease integrated biological and functional impairment staging framework.
Paulina Gonzalez‐Latapi +19 more
wiley +1 more source
Two new species of the genus <i>Morphostenophanes</i> Pic, 1925 from Yunnan, China (Coleoptera, Tenebrionidae, Stenochiinae, Cnodalonini). [PDF]
He H, Meng FY, Yang SJ.
europepmc +1 more source
ABSTRACT Objective Cognitive decline is a disabling and variable feature of Parkinson disease (PD). While cholinergic system degeneration is linked to cognitive impairments in PD, most prior research reported cross‐sectional associations. We aimed to fill this gap by investigating whether baseline regional cerebral vesicular acetylcholine transporter ...
Taylor Brown +6 more
wiley +1 more source
A new perspective on <i>Icriomastax</i> (Diptera: Tipulidae): phylogeny and description of five new species. [PDF]
Gouvêa J, Gil-Azevedo LH.
europepmc +1 more source
Multidimensional Profiling of MRI‐Negative Temporal Lobe Epilepsy Uncovers Distinct Phenotypes
ABSTRACT Objective Although hippocampal sclerosis (TLE‐HS) represents the most frequent cause of temporal lobe epilepsy (TLE), up to 30% of patients show no lesion on visual MRI inspection (TLE‐MRIneg). These cases pose diagnostic and therapeutic challenges and are underrepresented in surgical series.
Alice Ballerini +28 more
wiley +1 more source
Recognition and Risk: Ethnic Monitoring, Healthcare Access and Everyday Discrimination in Gypsy, Roma, and Traveller Communities in the UK. [PDF]
Molnár G +5 more
europepmc +1 more source
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao +6 more
wiley +1 more source
Expanding the horizon: Discovery of two new spider species of the <i>Pholcus phungiformes</i> species group (Araneae, Pholcidae) from Inner Mongolia, China, with a new western record for the group. [PDF]
Yan M, Liu Y, Wang L, Yao Z.
europepmc +1 more source
Location‐Specific Hematoma Volume Predicts Early Neurological Deterioration in Supratentorial ICH
ABSTRACT Objective Early neurological deterioration (END) adversely affects outcomes in patients with intracerebral hemorrhage (ICH). This study aimed to determine the location‐specific hematoma volumes for END in supratentorial ICH patients. Methods We retrospectively analyzed supratentorial ICH patients presenting from two prospective cohorts.
Zuoqiao Li +10 more
wiley +1 more source
AI-Driven Prediction of Chest CT Radiation Doses: Establishing BMI-Based Diagnostic Reference Levels and Patient-Factor Correlations for Machine-Learning Models. [PDF]
Hamd ZY +7 more
europepmc +1 more source

