Results 31 to 40 of about 20,912 (275)
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
McDonaldization of archives (an introduction to discussion)
Archeion, 2023 Macdonaldyzacja archiwów (wstęp do dyskusji) Artykuł stanowi analizę archiwów przez przyzmat stworzonej przez Georga Ritzera teorii makdonaldyzacji.
Hadrian Ciechanowski
doaj +1 more source
Advances in Solid‐Phase Processing Techniques: Innovations, Applications, and Future Perspectives
Advanced Materials Technologies, EarlyView.Based on practical manufacturing challenges, this review examines advanced solid‐phase processing techniques that overcome the inherent limitations of conventional melting‐based and traditional solid‐phase manufacturing, enabling the production of higher‐performance components at reduced cost through process innovation and improved supply‐chain ...
Tianhao Wang
wiley +1 more source
Advanced Science, EarlyView.ABSTRACT Organoid research offers valuable insights into human biology and disease, but reproducibility and scalability remain significant challenges, particularly for epithelial organoids. Here, we present an integrated microfluidic platform that addresses these limitations by enabling high‐throughput generation of uniform hydrogel microparticles ...
Barbora Lavickova +8 more
wiley +1 more source
Conflicts among Civilizations: The Influence behind War and Art [PDF]
, 2008 Why war or conflicts are fought between civilizations is a subject that could be debated with no end. The complexity of how our species reacts with each other and generates conflict exceeds the limitations of a single concept.
Pickett, Ross
core +1 more source
Glottodidactica, 2023 The objective of the article is to analyze the attitudes of foreign language teachers towards students’ mother tongues or heritage languages, as migrant students to the city of Gdańsk, Poland, use them as a compensation strategy in formal language ...
Hadrian Lankiewicz
doaj +1 more source
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.ABSTRACT In epidemiological studies, obsessive‐compulsive disorder (OCD) is robustly associated with increased risk of cardiometabolic disorders, including cardiovascular diseases, type 2 diabetes, and obesity. However, the mechanisms behind these associations are unclear. We conducted genetic correlation analyses to explore shared genetic etiology and
Robyn E. Wootton +217 more
wiley +1 more source
Annals of Neurology, EarlyView.Objective Impaired ability to induce stepping after incomplete spinal cord injury (SCI) can limit the efficacy of locomotor training, often leaving patients wheelchair‐bound. The cuneiform nucleus (CNF), a key mesencephalic locomotor control center, modulates the activity of spinal locomotor centers via the reticulospinal tract.
Anna‐Sophie Hofer +21 more
wiley +1 more source
Numismatic and archaeological collecting in northern Sicily during the first half of the nineteenth century [PDF]
, 2012 This research examines the archaeological protection system and antiquarian collecting in northern Sicily, in particular in the coastal strip from Palermo to Messina during the first half of the nineteenth century.
Crisa, Antonino
core
European Transport Research ReviewThe current paper was performed within the HADRIAN project and focuses on exploring the effects of innovative Human–Machine Interface (HMI) prototypes on safety, driving performance, and driver perceptions.
Marios Sekadakis +6 more
doaj +1 more source