Magnetic Resonance in Medicine, EarlyView.ABSTRACT Purpose Congenital heart disease affects 1% of US births, with some infants requiring cardiothoracic surgery under cardiopulmonary bypass (CPB). Optimal surgical parameters to minimize neuronal injury are unknown. We used serial 1H MRS in a neonatal CPB porcine model to assess acute neuronal damage and associated injury mechanisms.
Aaron Omon +5 more
wiley +1 more source
Interpretable artificial intelligence for predicting blood transfusion after surgery for femoral shaft fractures: A retrospective analysis. [PDF]
Indian J AnaesthManyam R +5 more
europepmc +1 more source
Endoscopic small bowel therapies for type 2 diabetes
Nutrition in Clinical Practice, EarlyView.Abstract Type 2 diabetes is a global epidemic despite current medical treatments. Many patients are not responsive to medications, and patients with obesity are hesitant about bariatric surgery. Studies investigating the metabolic effects of Roux‐en‐Y gastric bypass have increasingly demonstrated that the duodenum plays a key role in the ...
Roma Patel +4 more
wiley +1 more source
Seasonal Variations in Estimated Whole Blood Viscosity Associated with HbA1c: Evidence from Retrospective Pathology Review for Diabetes Management. [PDF]
Int J Mol SciMbah JI +4 more
europepmc +1 more source
Outcomes of Direct Vocal Fold Testosterone Injections in Hormone‐Naïve Adults: A Case Series
Otolaryngology–Head and Neck Surgery, EarlyView.Abstract Two nonbinary testosterone‐naïve individuals were seen at the Northwestern Memorial Hospital Voice Clinic. The objective was to determine the effectiveness of direct testosterone injections to the vocal folds for voice masculinization in testosterone‐naïve individuals.
Mariah E. Morton‐Jones +5 more
wiley +1 more source
Zegocractin for acute pancreatitis with systemic inflammatory response syndrome: a randomized, controlled, dose-ranging, phase 2b trial. [PDF]
EClinicalMedicineSutton R +11 more
europepmc +1 more source
Organ Medicine, EarlyView.This review evaluates how machine learning, multimodal integration, and generative AI optimize kidney transplant outcomes. These tools enable superior prediction and personalized therapy but face hurdles in data volume, generalizability, and ethics. Future clinical adoption depends on continued innovation and multidisciplinary collaboration to overcome
Maoxin Liao, Cheng Yang
wiley +1 more source
Method Comparison of Dried Blood Spot and Plasma Apolipoprotein B Measurement on a Semi-Automated Analyser: Toward Accessible Lipid Profiling in Resource-Limited Settings. [PDF]
Anal Sci AdvPitampersad B +4 more
europepmc +1 more source
Diagnosis and Management of Prenatal Hereditary Pyropoikilocytosis
Prenatal Diagnosis, EarlyView.ABSTRACT Hereditary pyropoikilocytosis (HPP) is a severe hemolytic anemia caused by variants in SPTA1, SPTB, and EPB41. These weaken horizontal interactions in the erythrocyte cytoskeleton, causing membrane fragmentation and splenic sequestration. It will readily cause fetal anemia and often hydrops fetalis. Prenatal diagnosis requires first ruling out
Connor Hartzell +6 more
wiley +1 more source
Pediatric Investigation, EarlyView.This evidence map of 63 studies (n = 6158) showed growth hormone therapy in children with growth hormone deficiency has neutral glucose effects, mixed lipid outcomes, potential benefits for bone mineral density, bone mineral content, and parathyroid hormone, but generally no impact on thyroid function, body composition, or body mass index.
Wei Wu +6 more
wiley +1 more source