Results 141 to 150 of about 400,704 (247)
Extraction and amplification of DNA from archival haematoxylin and eosin sections and cervical cytology Papanicalaou smears [PDF]
D P, Jackson +6 more
openaire +2 more sources
Mr BMT Achieves Systemic Macrophage Replacement With Preservation of Tissue Homeostasis
Microglia replacement by bone marrow transplantation (Mr BMT) enables systemic replacement of tissue‐resident macrophages. Despite persistent macrophage and tissue remodeling across multiple organs, core biological functions and innate immune responses remain preserved, supporting long‐term maintenance of organismal homeostasis and the therapeutic ...
Yufei Xu +17 more
wiley +1 more source
Lactate in cervical cancer induces HNRNPU K181 lactylation, opposed by NAA50‐mediated acetylation and suppressed by Pazopanib. This lactylation enhances HNRNPU binding to PHGDH pre‐mRNA exon 1, maintaining exon 1‐containing transcripts and mRNA stability, thereby activating serine metabolism.
Chang Zhang +6 more
wiley +1 more source
Urachal Mucinous Cystic Tumour of Low Malignant Potential With Incidental Clinical Presentation: A Case Report With Clinicopathologic Features and Review of the Literature. [PDF]
Miller A, Saxena M.
europepmc +1 more source
The hyperactivation of PI3K/AKT signaling in PTEN wild‐type triple‐negative breast cancer represents a clinical paradox. We delineate a novel post‐translational regulatory axis wherein the oncogene TSPYL5 competitively antagonizes the deubiquitinase USP10.
Jiaying Shi +8 more
wiley +1 more source
An iodine-based formulation of a simple boiling water extract of Hibiscus sabdariffa was compounded and stored at 4oC. Formalin fixed paraffin embedded blocks of tissues from appendix, ovary, lymph node and skin were randomly retrieved from teaching ...
Benard S.A.1*, Amusan O.S.1, Fowotade A.A. 1, Afolabi O.O.2, Olutunde O.A1.
doaj
Inflammatory bowel disease (IBD) pathogenesis remains unclear. This study reveals that thymus‐originated IL‐7R‐enriched extracellular vesicles exacerbate colitis by promoting neutrophil extracellular traps via a thymus‐gut axis, uncovering an inter‐organ communication mechanism in inflammatory bowel disease pathogenesis.
Yao Liao +21 more
wiley +1 more source
Assessing the Safety of Carbon Dioxide Extracts of <i>Acorus calamus</i> Rhizomes and <i>Calendula officinalis</i> Flowers and the Antitussive Activity of the Tablet Dosage Form 'Exkair' and Granules 'Zerp-Ak-Broncho' Developed on Their Basis. [PDF]
Ibadullayeva G +10 more
europepmc +1 more source
m6A‐Mediated Glycolysis by IL‐37 Drives T Cell Metabolic Reprogramming to Regulate Colitis
This study identifies an IL‐37/SIGIRR‐METTL14 regulatory axis that suppresses global m6A modification in CD4+ T cells. IL‐37 signaling, mediated through SIGIRR, inhibits IRAK4 and JNK phosphorylation, leading to downregulation of the methyltransferase METTL14.
Xiaoyan Wang +26 more
wiley +1 more source

