Results 31 to 40 of about 429,520 (307)

CXCR2 deficient mice display macrophage-dependent exaggerated acute inflammatory responses [PDF]

, 2017
CXCR2 is an essential regulator of neutrophil recruitment to inflamed and damaged sites and plays prominent roles in inflammatory pathologies and cancer. It has therefore been highlighted as an important therapeutic target.
A Mantovani, A Rot, A Rot, A Zlotnik, A Zlotnik, AA Filardy, AE Cardona, AEI Proudfoot, C Schinke, D Marvel, DI Gabrilovich, F Bachelerie, F Balkwill, F Porcheray, F Sallusto, FR Balkwill, G Cacalano, H Saiwai, HM Baldwin, J Dalli, J Schindelin, J Yang, J-I Youn, J-I Youn, K Kishida, KM Hertzer, L Liu, M-C Lo, MK Ho, O Soehnlein, P Ranganathan, P Scapini, RA Navarro-Xavier, RM Devalaraja, S Milatovic, T Jamieson, T Jamieson, T Kakinuma, TJ Schall   +38 more
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Prognostic and predictive value of a pathomics signature in gastric cancer

Nature Communications, 2022
The current tumour-node-metastasis staging system alone cannot provide adequate information for prognosis and adjuvant chemotherapy benefits in patients with gastric cancer. Herein, the authors propose a pathomics signature that was derived from multiple
Dexin Chen, Meiting Fu, Liangjie Chi, Liyan Lin, Jiaxin Cheng, Weisong Xue, Chenyan Long, Wei Jiang, Xiaoyu Dong, Jian Sui, Dajia Lin, Jianping Lu, Shuangmu Zhuo, Side Liu, Guoxin Li, Gang Chen, Jun Yan   +16 more
doaj   +1 more source

A colour preference technique to evaluate acrylamide-induced toxicity in zebrafish [PDF]

, 2017
The zebrafish has become a commonly used vertebrate model for toxicity assessment, of particular relevance to the study of toxic effects on the visual system because of the structural similarities shared by zebrafish and human retinae. In this article we
Albalawi, Aishah, Jia, Laibing, Raghupathy, Rakesh Kotapati, Reilly, James, Shu, Xinhua, Xiao, Qing, Zhao, Zhenkai   +6 more
core   +3 more sources

Correction: Corrigendum: Systematic pan-cancer analysis of tumour purity

Nature Communications, 2016
Nature Communications 6 Article number: 8971 (2015); Published 4 December 2015; Updated 5 February 2016 In the Results section of this Article, haematoxylin and eosin staining data from the TCGA repository are incorrectly referred to as ...
Dvir Aran, Marina Sirota, Atul J. Butte
doaj   +1 more source

High fat diet attenuates the anticontractile activity of aortic PVAT via a mechanism involving AMPK and reduced adiponectin secretion [PDF]

, 2018
Background and aim: Perivascular adipose tissue (PVAT) positively regulates vascular function through production of factors such as adiponectin but this effect is attenuated in obesity.
Alganga, Husam, Almabrouk, Tarek A.M., Guzik, Tomasz J., Katwan, Omar J., Kennedy, Simon, Salt, Ian P., Skiba, Dominik S., Touyz, Rhian M., Ugusman, Azizah B., White, Anna D.   +9 more
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Beetroot and Turmeric as Alternative Dyes for Haematoxylin and Eosin in Histological Staining

Scientific Research Journal of Clinical and Medical Sciences, 2022
Dyes are referred to as stains which are used to add color to tissues and microbes to make them optical distinct. The dyes are both synthetic and natural, the synthetic ones may be harmful, hazardous to health and are costly to obtain. Natural dyes are eco-friendly, not costly and not hazardous to health as compared to synthetic dyes.
Joyce Achagh, Saul Gontewa Amunum, Maduka Ukpabi, Bala Nuhu Yusuf, Bola Deko, Obiora Ejinaka, Godfrey Dajok, Uchejeso Obeta   +7 more
openaire   +1 more source

Deep Learning-Based Microscopic Diagnosis of Odontogenic Keratocysts and Non-Keratocysts in Haematoxylin and Eosin-Stained Incisional Biopsies

Diagnostics, 2021
Background: The goal of the study was to create a histopathology image classification automation system that could identify odontogenic keratocysts in hematoxylin and eosin-stained jaw cyst sections.
Roopa S. Rao, Divya B. Shivanna, Kirti S. Mahadevpur, Sinchana G. Shivaramegowda, Spoorthi Prakash, Surendra Lakshminarayana, Shankargouda Patil   +6 more
doaj   +1 more source

The hepatic sympathetic nerve plays a critical role in preventing Fas induced liver injury in mice [PDF]

, 2005
Background: Although previous studies have shown that the hepatic sympathetic nerve controls various physiological functions in the liver, the role of this nerve in liver injury has yet to be clarified.Aims: The purpose of this study was to elucidate the
Chida, Y, Kubo, C, Sudo, N, Takaki, A
core   +1 more source

Genetic background influences tumour development in heterozygous Men1 knockout mice [PDF]

, 2020
Multiple endocrine neoplasia type 1 (MEN1), an autosomal dominant disorder caused by MEN1 germline mutations, is characterised by parathyroid, pancreatic and pituitary tumours. MEN1 mutations also cause familial isolated primary hyperparathyroidism (FIHP)
Christie, Paul T., Javid, Mahsa, Kooblall, Kreepa G., Lines, Kate E., Mallon, Ann-Marie, Newey, Paul J., Piret, Sian E., Reed, Anita Ac, Simon, Michelle, Stevenson, Mark, Thakker, Rajesh V., Walls, Gerard V.   +11 more
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Ovarian cancer: diagnostic accuracy and tumor types distribution in East Africa compared to North America

Diagnostic Pathology, 2020
Background Ovarian cancer is a spectrum of several histologically distinct tumor types that differ in etiology, response to therapy, and prognosis. In resource-limited settings, the diagnosis of ovarian cancer can be challenging. This study describes the
Peter F. Rambau, Martin Köbel, Derek Tilley, Alex Mremi, Robert Lukande, William Muller   +5 more
doaj   +1 more source