Results 51 to 60 of about 429,520 (307)

Intestinal intussusception in an adult caused by helminthic parasitosis [PDF]

, 2016
Intestinal intussusception is an uncommon acute condition in adults and is most commonly caused by an intestinal tumor mass. Helminthic parasitosis is a widespread infection in Africa, and the load of worms is often high in individuals living in areas ...
Ciardi, Gaia, Ogwang, David M., Okello, Tom R., Opira, Cyprian, Pecorella, Irene   +4 more
core   +2 more sources

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

Molecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet   +17 more
wiley   +1 more source

Modified Cajal's trichrome stain as a diagnostic aid in the study of epithelial pathology

Indian Journal of Pathology and Microbiology, 2017
Background: Diagnosis of initial epithelial pathology maybe difficult in Squamous Cell Carcinoma (SCC), Carcinoma In Situ and other atypical epithelial malignancies, under routine Haematoxylin and Eosin (H and E) stain.
Karpagaselvi Sanjai, Anjum Baker, Lokesh Papiah Reddy, Bhavna Pandey   +3 more
doaj   +1 more source

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

Molecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad, Marie Austdal, Oddmund Nordgård, Gunnar Mellgren, Satu Oltedal, Marie L. Austbø, Ylva H. Vignes, Thomas Helland, Kristin Jonsdottir, Tone H. Lende, Emilius A. M. Janssen, Bjørnar Gilje, Kjersti Tjensvoll, PBCB study group, Gunnar Mellgren, Tone Hoel Lende, Anette Heie, Kristin Viste, Anita Røyneberg Alvheim, Emiel AM Janssen, Kristin Jonsdottir, Ann Cathrine Kroksveen, Thomas Helland, Einar Gudlaugsson, Oddmund Nordgård, Satu Oltedal, Kristin Løge Aanestad, Jan Terje Kvaløy, Kirsten Lode, Kari Britt Hagen, Marie Austdal, Ylva H. Vignes, Siri Tungland Sola, Nina Egeland Amundsen, Finn Magnus Eliassen, Emeritus Ernst A Lien   +35 more
wiley   +1 more source

Regressive Hibiscus sabdariffa Extract Nuclear Stain Using Formalin Fixed Paraffin Embedded Skin, Lymph node and Appendix

Sokoto Journal of Medical Laboratory Science, 2020
A simple boiling water extract of Hibiscus sabdariffa was compounded with 10% ferric chloride solution, sodium chloride and glacial acetic acid and stored at 4 o C.
Olufunmilayo, O.A. , Benard, S.A.* , Balogun, M. O. , Fowotade, A.A. , Olutunde, O.A ., Afolabi, O.O.
doaj  

Diagnosis of Basal Cell Carcinoma with Ex-vivo Confocal Laser Scanning Microscopy in a Real-life Setting

Acta Dermato-Venereologica, 2023
Ex-vivo confocal laser scanning microscopy provides a rapid alternative to routine histological processing using haematoxylin and eosin-stained sections. Previous studies suggest high diagnostic accuracy in basal cell carcinoma.
Stephan Forchhammer, Sonja Grunewald, Matthias Möhrle, Gisela Metzler, Thomas Eigentler, Anne-Kristin Münch, Hanna Ogrzewalla   +6 more
doaj   +1 more source

Pollens destroy respiratory epithelial cell anchors and drive alphaherpesvirus infection [PDF]

, 2019
Pollens are well-known triggers of respiratory allergies and asthma. The pollen burden in today's ambient air is constantly increasing due to rising climate change and air pollution.
Gevaert, Kris, Impens, Francis, Laval, Kathlyn, Nauwynck, Hans, Poelaert, Katrien, Van Cleemput, Jolien, Van Den Broeck, Wim   +6 more
core   +3 more sources

Stain Removal Through Color Normalization of Haematoxylin and Eosin Images: A Review

Journal of Physics: Conference Series, 2019
Abstract Histopathology images are used for the diagnosis and examination of cancer cells. Preparing and scanning histopathology slides consist of numerous steps of which staining are an important process. But these staining procedures cause multitude problems as there may be variations in the slides due to multiple reasons.
B. Lakshmanan, S. Anand, T. Jenitha
openaire   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Changes in the anti-inflammatory activity of soy isoflavonoid genistein versus genistein incorporated in two types of cyclodextrin derivatives

Chemistry Central Journal, 2012
Background The isoflavonoid genistein represents the major active compound from soybean, the vegetal product from Glycine max (Fabaceae). The aim of this study is to prove that genistein was incorporated in two semisynthetic cyclodextrins, beta ...
Danciu CorinaTiulea, Soica Codruta, Csanyi Erzsebet, Ambrus Rita, Feflea Stefana, Peev Camelia, Dehelean Cristina   +6 more
doaj   +1 more source