Results 81 to 90 of about 429,520 (307)

A macroprolactinoma becoming resistant to cabergoline and developing atypical pathology [PDF]

, 2016
Pituitary adenomas are a common intracranial neoplasm, usually demonstrating a benign phenotype. They can be classified according to pathological, radiological or clinical behaviour as typical, atypical or carcinomas, invasive or noninvasive, and ...
Ansorge, Olaf, Cudlip, Simon, Farah, George, Fathelrahman, Ahmed, Grossman, Ashley B, Karavitaki, Niki, Sbardella, Emilia   +6 more
core   +3 more sources

Effect of water softening on the colour intensity of routine haematoxylin and eosin stain

Eastern Mediterranean Health Journal, 2003
Haematoxylin and eosin [H and E] is the most popular routine stain used in pathology laboratories for highlighting cellular structures. To study the effect of tap water’softening’ [i. e. calcium extraction] on H and E stains, 5 sets of slides from 30 different paraffin-embedded human pathologic tissue blocks were prepared in the same way except for ...
S R, Malkawi, R M, Abu-Hazeem, M O, Easa
openaire   +2 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Quantitative assessment of H&E staining for pathology: development and clinical evaluation of a novel system

Diagnostic Pathology
Background Staining tissue samples to visualise cellular detail and tissue structure is at the core of pathology diagnosis, but variations in staining can result in significantly different appearances of the tissue sample.
Catriona Dunn, David Brettle, Martin Cockroft, Elizabeth Keating, Craig Revie, Darren Treanor   +5 more
doaj   +1 more source

Atherosclerotic carotid plaque composition: a 3T and 7T MRI-histology correlation study [PDF]

, 2016
Background and Purpose Carotid artery atherosclerotic plaque composition may influence plaque stability and risk of thromboembolic events, and non-invasive plaque imaging may therefore permit risk stratification for clinical management.
Condon, B., Foo, S.Y., Forbes, K.P., Holmes, W.M., Lopez Gonzalez, M.R., Muir, K.W., Stewart, W., Welch, G.   +7 more
core   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Staining Potentials of Indigenous Hibiscus Sabdariffa Calyx and Lawsonia inermis Leaves on Liver and Kidney Tissues

Sokoto Journal of Medical Laboratory Science, 2020
In view of the hazards associated with the use of synthetic stains and the escalating cost of foreign dyes, it has become essential to seek for natural, economic, easy to use, biodegradable, safe (to both human and environmental health) and more eco ...
Okolie, N. ; Ngokere, A. and Enweani, I.
doaj  

Cartilaginous metaplasia of varicose veins: a case report [PDF]

, 2013
Cartilaginous metaplasia of superficial veins was found in a 64-year-old woman who underwent surgery for varicose veins. At operation, some varicose veins of the medial thigh were semi-rigid and fibroelastic to the touch. Histology revealed that half the
CAGGIATI, Alberto, FRANCESCHINI, MARCO
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Microscopy with ultraviolet surface excitation for rapid slide-free histology. [PDF]

, 2017
Histologic examination of tissues is central to the diagnosis and management of neoplasms and many other diseases, and is a foundational technique for preclinical and basic research.
Bishop, John, Borowsky, Alexander D, Demos, Stavros G, Fereidouni, Farzad, Harmany, Zachary T, Kintner, John A, Lechpammer, Mirna, Levenson, Richard, McPherson, John D, Tian, Miao, Todd, Austin   +10 more
core   +2 more sources