Results 81 to 90 of about 400,704 (247)

A Comparative Evaluation of Beta Vulgaris and Zingiber officinale Staining with Conventional Haematoxylin and Eosin: An Experimental Study [PDF]

Journal of Clinical and Diagnostic Research
Introduction: Exfoliative cytological staining is a fundamental technique in pathology, providing contrast to cellular components for microscopic examination.
Sangeetha Ramu, Inchara
doaj   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

SPG4 and Dementia: Expanding the Clinical Spectrum

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza, Arun Meyyazhagan, Eliseo Picchi, Gustavo Ribas, Ingrid Faber, Ryosuke Miyamoto, Preethi Basavaraju, Paolo Eusebi, Haripriya Kuchi Bhotla, Mario Stasi, Fabrizio Gaudiello, Francesco Patti, Filippo Maria Santorelli, Marcondes Cavalcante França Jr, José Luiz Pedroso, Orlando Graziani Povoas Barsottini, Hélio Afonso Ghizoni Teive, Peter Henry St George‐Hyslop, Toshitaka Kawarai, Antonio Orlacchio   +19 more
wiley   +1 more source

Patch-to-slide fusion deep learning model for histological diagnosis of early pregnancy loss including hydatidiform mole

npj Digital Medicine
Distinguishing histological subtypes of early pregnancy loss is crucial for clinical practice. Current gold standards combining pathological and molecular profiling are costly, limiting implementation.
Yating Zhao, Xinhui He, Xin Ye, Zhe Wang, Bo Huang, Jiaqi Ning, Limeng Cai, Peilin Han, Huifang Zhang, Hao Chen, Xiangang Yin, Jie Dong, Ping Duan, Huafeng Shou, Qingmei Han, Kai Yan, Jing Zhang, Min Hu, Ruiqi Sun, Qihong Wan, Xiupu Liu, Qiwei Zheng, Wanting Huang, Haixia Luo, Jue Xie, Xiaofei Zhang, Xiang Tian, Jianhua Qian   +27 more
doaj   +1 more source

Assessment of the Effectiveness of Xylene-free Haematoxylin and Eosin Staining versus the Conventional Approach: A Comparative Observational Study [PDF]

Journal of Clinical and Diagnostic Research
Introduction: Xylene, a commonly used hydrocarbon in histopathological laboratories, poses significant risks, including carcinogenicity. Identifying safer alternatives is essential for laboratory safety and environmental sustainability. Aim: To evaluate
Swetha Muralidharan, Sangeetha Nagalingam, Shimi Sunder Raja Kumar   +2 more
doaj   +1 more source

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source

Cover Page Health Res. Afr: Vol 4; (7), July 2026

Health Research in Africa
Illustrations of the cover page, from top to bottom 1: Zingiber officinale (Ginger) 2: Total hysterectomy for uterine sarcoma: Haematoxylin and eosin staining.
Samuel Nko'o Amvene
doaj   +1 more source

Strain‐Programmable Luminescent Adhesive Patch With Tartrazine‐Mediated Optical Skin Clearing for Photochemical Tissue Bonding

Advanced Functional Materials, EarlyView.
We propose a suture‐complementary approach that integrates optical skin clearing with a strain‐programmable luminescent adhesive patch. Hyaluronic acid promotes transdermal delivery of tartrazine to improve optical clearing and stabilizes its interaction with a photosensitizer. Optical clearing increases the penetration depth of visible light into skin,
Seong‐Jong Kim, Kyungjoo Jo, Kwanghyeon Park, Jun Hee Kim, Jong Hyeong Cho, Inhoo Choi, Sei Kwang Hahn   +6 more
wiley   +1 more source

Reducing technical variability in image analyses of haematoxylin and eosin stained tissues

Bio-Algorithms and Med-Systems
<br><b>Objective:</b> The aim of this study is to develop and evaluate a preprocessing pipeline aimed at reducing technical variability in histomic features extracted from whole-slide images (WSIs) of endometrial cancer tissue using foundation models, thus improving the reliability and generalizability of downstream computational ...
Julia Merta, Milosz Pietrus, Iwona Gawron, Michal Marczyk   +3 more
openaire   +2 more sources

Implantable Ionic Memristors Based on Natural Polymer Heterojunctions

Advanced Functional Materials, EarlyView.
We report an implantable natural polymer‐based ionic memristor composed of hyaluronic acid, chitosan, and PDMS. The device achieved 98.94% accuracy in MNIST classification while reducing training time by 36.8% compared with a conventional artificial neural network (ANN).
Dong‐yup Lee, Byung Ik Park, Gihyeon Yim, Hyunjae Yoo, Sangjun Ma, Jundong Park, Jeong‐Yun Sun   +6 more
wiley   +1 more source