Results 181 to 190 of about 17,460 (230)
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Synergism of macrocyclic lactones against Haemonchus contortus
Parasitology Research, 2023A possible synergistic effect of macrocyclic lactones' (MLs) combination has been previously described against resistant gastrointestinal nematodes of cattle. In addition to synergism, drug-drug interactions between MLs can also result in additive or antagonistic effect, considering the different MLs pharmacokinetics, pharmacodynamics, and interactions
Matheus Takemi Muchon Nakatani +8 more
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Haemonchus contortus microtubules are cold resistant
Molecular and Biochemical Parasitology, 2014Haemonchus contortus is an important nematode of livestock that is present in most parts of the world. The life cycle comprises free living stages (egg, L1, L2 and L3 larvae), and parasitic stages (L4, adult and egg) in a ruminant. Microtubules are filamentous structures which are made from polymerization of α- and β-tubulin. In vitro polymerization of
Shoaib Ashraf, Roger K. Prichard
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Levamisole binding sites in Haemonchus contortus
International Journal for Parasitology, 1998Larval and adult extracts from isolates of Haemonchus contortus were assayed for specific [3H]levamisole binding activity. All of the tissue preparations displayed [3H]levamisole binding sites. The sensitive isolate SE and resistant isolate RJ showed no differences in larval and adult binding data. Larval SE extracts had higher receptor density (Bmax =
M J, Moreno-Guzmán +5 more
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Resistance of Haemonchus contortus to thiophanate
Research in Veterinary Science, 1980The occurrence of a field strain of Haemonchus contortus which was resistant to thiophanate and susceptible to thiabendazole and levamisole is reported. The LD95 of thiophanate for the strain was found to be 156.1 mg/kg and its resistance factor was 6.7.
J R, Edwards, G, De Chaneet
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Progress on vaccination against Haemonchus contortus
International Journal for Parasitology, 1995Control of Haemonchus contortus at present is largely by the use of anthelmintics, assisted in some regions by management programs. Widespread development of resistance, particularly in South Africa and Australia, and concerns associated with the manufacture and use of chemicals have led to increasing interest in vaccination as an alternative means of ...
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Haemonchus contortus: Food of preinfective larvae
Experimental Parasitology, 1971Abstract Haemonchus contortus eggs were bacterially sterilized and cultivated in three different preparations of Escherichia coli cultures and a nutrient broth at 30 C for 7 days. The following percentages of infective larvae were recovered: supernatant fluid from E. coli culture, 0%; washed E. coli , 71%; heat-killed E.
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Immunity to Haemonchus contortus and Vaccine Development
2016Sheep are capable of developing protective immunity to Haemonchus contortus through repeated exposure to this parasite, although this immune protection is the result of a complex interaction among age, gender, physiological status, pregnancy, lactation, nutrition and innate and adaptive immunity in the host animal.
Nisbet, A. J. +3 more
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Inheritance of Cambendazole Resistance in Haemonchus contortus
American Journal of Veterinary Research, 1981SUMMARY Fourth-molt larvae (M4) of cambendazole-resistant (CBZ-R) and cambendazole-susceptible (BPL) strains of Haemonchus contortus were recovered from donor lambs and inoculated orally into source lambs to effect mating in a 2nd lamb. Eggs produced by these parasitic matings were collected, cultured, and inoculated into lambs to compare the ...
H, Herlich, R S, Rew, M L, Colglazier
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Experimental Haemonchus contortus infections in guinea pigs
International Journal for Parasitology, 1989Approximately 40% of exsheathed Haemonchus contortus larvae administered to guinea pigs established in the stomach and developed into fourth stage larvae. Most worms were then lost between 5 and 7 days after infection and the guinea pigs were resistant to a second infection.
Wagland, B.M. +3 more
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Haemonchus contortus: Cloning and characterization of serpin
Experimental Parasitology, 2010The serpin gene of Haemonchus contortus (hc-serpin) was cloned and characterized in this study. Specific primers for rapid amplification cDNA ends (RACE) were designed based on the expression sequence tag (EST, BM173953) to amplify the 3'- and 5'-ends of hc-serpin. The full length of the cDNA of this gene was obtained by overlapping the sequences of 3'-
Daosheng, Yi +3 more
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