Novel expression of Haemonchus contortus vaccine candidate aminopeptidase H11 using the free-living nematode Caenorhabditis elegans [PDF]
With the problem of parasitic nematode drug resistance increasing, vaccine development offers an alternative sustainable control approach. For some parasitic nematodes, native extracts enriched for specific proteins are highly protective.
Antonopoulos, A. +8 more
core +3 more sources
The potential to control Haemonchus contortus in indigenous South African goats with copper oxide wire particles [PDF]
The high prevalence of resistance of Haemonchus contortus to all major anthelmintic groups has prompted investigations into alternative control methods in South Africa, including the use of copper oxide wire particle (COWP) boluses.
Vatta, A. F. +3 more
core +2 more sources
Increased expression of a microRNA correlates with anthelmintic resistance in parasitic nematodes [PDF]
Resistance to anthelmintic drugs is a major problem in the global fight against parasitic nematodes infecting humans and animals. While previous studies have identified mutations in drug target genes in resistant parasites, changes in the expression ...
Bartley, David +13 more
core +2 more sources
A conserved metalloprotease mediates ecdysis in Caenorhabditis elegans [PDF]
Molting is required for progression between larval stages in the life cycle of nematodes. We have identified four mutant alleles of a <i>Caenorhabditis elegans</i> metalloprotease gene, <i>nas-37</i>, that cause incomplete ...
Birnie, A.J. +4 more
core +1 more source
Recombinant expression systems: the obstacle to helminth vaccines? [PDF]
A
Claerebout, Edwin +3 more
core +2 more sources
The kunitz domain protein BLI-5 plays a functionally conserved role in cuticle formation in a diverse range of nematodes [PDF]
The cuticle of parasitic nematodes performs many critical functions and is essential for proper development and for protection from the host immune response.
Antony P. Page +43 more
core +1 more source
The evolutionary success of parasitic worms causes significant economic losses and animal health problems, including in the small ruminant industry. The hematophagous nematode Haemonchus contortus is a common endoparasite that infects wild and domestic ...
Isabella Adduci +6 more
doaj +1 more source
The purpose of this study was to ascertain how the concentration of the ethyl acetate component of calabash fruit (Crescentia cujete L.) affected the in vitro mortality of the Haemonchus contortus worm.
Dyah Ajeng Suhita +4 more
doaj +1 more source
Anthelmintic acetogenin from Annona squamosa L. Seeds
Annona squamosa seeds extracts showed anthelmintic activity against Haemonchus contortus, the main nematode of sheep and goat in Northeastern Brazil. A compound 1 was isolated from ethyl acetate extract and inhibited the egg hatching of H.
Marta M.C. Souza +5 more
doaj +1 more source
Genomic introgression mapping of field-derived multiple-anthelmintic resistance in Teladorsagia circumcincta [PDF]
Preventive chemotherapy has long been practiced against nematode parasites of livestock, leading to widespread drug resistance, and is increasingly being adopted for eradication of human parasitic nematodes even though it is similarly likely to lead to ...
Bisset, Stewart A +6 more
core +4 more sources

