Results 31 to 40 of about 7,153 (69)

Sub-lethal doses of albendazole induce drug metabolizing enzymes and increase albendazole deactivation in Haemonchus contortus adults

Veterinary Research, 2020
The efficacy of anthelmintic therapy of farm animals rapidly decreases due to drug resistance development in helminths. In resistant isolates, the increased expression and activity of drug-metabolizing enzymes (DMEs), e.g.
Pavlína Kellerová, Lucie Raisová Stuchlíková, P. Matoušková, Karolína Štěrbová, J. Lamka, M. Navrátilová, I. Vokřál, B. Szotáková, L. Skálová   +8 more
semanticscholar   +1 more source

Frequency of Resistance to Benzimidazoles of Haemonchus contortus Helminths from Dairy Sheep, Goats, Cattle and Buffaloes in Greece

Pathogens, 2020
The study investigated the presence of resistance to benzimidazoles in Haemonchus contortus helminths from ruminant species in Greece through the detection of the Phe/Tyr polymorphism in the amino acid at position 200 of the β-tubulin protein.
K. Arsenopoulos, S. Minoudi, I. Symeonidou, A. Triantafyllidis, A. Katsafadou, D. T. Lianou, G. Fthenakis, E. Papadopoulos   +7 more
semanticscholar   +1 more source

Nematicidal activity of aqueous tinctures of medicinal plants against larvae of the nematodes Strongyloides papillosus and Haemonchus contortus

, 2020
The study focuses on in vitro effect of aqueous tinctures of 48 species of herbaceous, shrub and tree plants on the first-third stage larvae of Strongyloides papillosus (Wedl, 1856) and third-stage larvae of Haemonchus contortus (Rudolphi, 1803) Cobb ...
O. Boyko, A. Kabar, V. Brygadyrenko
semanticscholar   +1 more source

Variation in gut bacterial composition is associated with Haemonchus contortus parasite infection of sheep

Animal Microbiome, 2020
One of the greatest impediments to global small ruminant production is infection with the gastrointestinal parasite, Haemonchus contortus. In recent years there has been considerable interest in the gut microbiota and its impact on health.
Md. Abdullah Al Mamun, M. Sandeman, P. Rayment, P. Brook-Carter, E. Scholes, N. Kasinadhuni, D. Piedrafita, A. Greenhill   +7 more
semanticscholar   +1 more source

The global diversity of Haemonchus contortus is shaped by human intervention and climate

Nature Communications, 2019
Haemonchus contortus is a haematophagous parasitic nematode of veterinary interest. We have performed a survey of its genome-wide diversity using single-worm whole genome sequencing of 223 individuals sampled from 19 isolates spanning five continents. We
Guillaume Sallé, S. Doyle, J. Cortet, J. Cabaret, M. Berriman, Nancy E. Holroyd, J. Cotton   +6 more
semanticscholar   +1 more source

Lipid composition and abundance in the reproductive and alimentary tracts of female Haemonchus contortus

Parasites & Vectors, 2020
Lipids play essential structural and functional roles in the biology of animals. Studying the composition and abundance of lipids in parasites should assist in gaining a better understanding of their molecular biology, biochemistry and host-parasite ...
Tao Wang, Guangxu Ma, S. Nie, N. Williamson, G. E. Reid, R. Gasser   +5 more
semanticscholar   +1 more source

Characterization of the Complete Mitochondrial Genomes of Two Sibling Species of Parasitic Roundworms, Haemonchus contortus and Teladorsagia circumcincta

Frontiers in Genetics, 2020
Haemonchus contortus and Teladorsagia circumcincta are among the two most pathogenic internal parasitic nematodes infecting small ruminants, such as sheep and goats, and are a global animal health issue.
Nikola Palevich, P. Maclean, Young-Jun Choi, M. Mitreva   +3 more
semanticscholar   +1 more source

Biomedical Evaluation of Lansium parasiticum Extract-Protected Silver Nanoparticles Against Haemonchus contortus, a Parasitic Worm

Frontiers in Molecular Biosciences, 2020
Here we show the novel anti-helminthic potential of Lansium parasiticum aqueous extract-protected silver nanoparticles (LAgNPs) against albendazole-resistant gastrointestinal parasite Haemonchus contortus.
Vanshita Goel, P. Kaur, L. Singla, Diptiman Choudhury   +3 more
semanticscholar   +1 more source

Immunization of Goats with Recombinant Protein 14-3-3 Isoform 2(rHcftt-2) Induced Moderate Protection against Haemonchus contortus Challenge

Pathogens, 2020
A previous study identified that isoform 2 (Hcftt-2) of the 14-3-3 protein of Haemonchus contortus (H. contortus) could suppress immune functions of goat peripheral blood mononuclear cells (PBMCs) and might be a potential vaccine target, as ...
Yongqian Bu, Caiwen Jia, Xiaowei Tian, Kalibixiati Aimulajiang, M. Memon, Ruofeng Yan, Xiaokai Song, Lixin Xu, Xiangrui Li   +8 more
semanticscholar   +1 more source

First report of multiple resistance to eprinomectin and benzimidazole in Haemonchus contortus on a dairy goat farm in France.

Parasitology international, 2020
Pour-on eprinomectin was recently registered for lactating small ruminants. Given the high prevalence of benzimidazole resistance in gastrointestinal nematodes in dairy goats, many farmers use eprinomectin exclusively to treat their animals.
L. Bordes, N. Dumont, A. Lespine, Elise Souil, J. Sutra, F. Prévot, C. Grisez, Lola Romanos, Aurélie Dailledouze, P. Jacquiet   +9 more
semanticscholar   +1 more source