Results 41 to 50 of about 7,153 (69)

RIG-I has a role in immunity against Haemonchus contortus, a gastrointestinal parasite in Ovis aries- a novel report

bioRxiv, 2020
RIG-I is associated to the DExD/H box RNA Helicases. It is a Pattern Recognition Receptor (PRR), playing a crucial role in the system and is a germ line encoded host sensor to perceive Pathogen Associated Molecular Patterns or PAMPs.
Samiddha Banerjee, A. Pal, A. Pal, S. Mandal, P. Chatterjee, J. Chatterjee   +5 more
semanticscholar   +1 more source

Similarities and differences in the biotransformation and transcriptomic responses of Caenorhabditis elegans and Haemonchus contortus to five different benzimidazole drugs

International Journal for Parasitology: Drugs and Drug Resistance, 2019
We have undertaken a detailed analysis of the biotransformation of five of the most therapeutically important benzimidazole anthelmintics - albendazole (ABZ), mebendazole (MBZ), thiabendazole (TBZ), oxfendazole (OxBZ) and fenbendazole (FBZ) - in ...
Susan Stasiuk, G. Macnevin, M. Workentine, D. Gray, E. Redman, David J. Bartley, A. Morrison, N. Sharma, D. Colwell, D. Ro, J. S. Gilleard   +10 more
semanticscholar   +1 more source

Dafachronic acid promotes larval development in Haemonchus contortus by modulating dauer signalling and lipid metabolism

PLoS Pathogens, 2019
Here, we discovered an endogenous dafachronic acid (DA) in the socioeconomically important parasitic nematode Haemonchus contortus. We demonstrate that DA promotes larval exsheathment and development in this nematode via a relatively conserved nuclear ...
Guangxu Ma, Tao Wang, Pasi K. Korhonen, N. Young, S. Nie, C. Ang, N. Williamson, G. E. Reid, R. Gasser   +8 more
semanticscholar   +1 more source

Signatures of selection for resistance to Haemonchus contortus in sheep and goats

BMC Genomics, 2019
Gastrointestinal nematode infection (GNI) is the most important disease affecting the small ruminant industry in U.S. The environmental conditions in the southern United States are ideal for the survival of the most pathogenic gastrointestinal nematode ...
Z. Estrada-Reyes, Y. Tsukahara, R. Amadeu, A. Goetsch, T. Gipson, T. Sahlu, R. Puchala, Zaisen Wang, S. Hart, R. Mateescu   +9 more
semanticscholar   +1 more source

Differences in immune responses to Haemonchus contortus infection in the susceptible Ile de France and the resistant Santa Ines sheep under different anthelmintic treatments regimens

Veterinary Research, 2019
Understanding the immunological basis of resistance to gastrointestinal nematode infections in livestock is important in order to develop novel methods of parasite control such as vaccination or genetic selection for parasite resistance.
A. Albuquerque, C. C. Bassetto, F. A. Almeida, Katie A. Hildersley, T. McNeilly, C. Britton, A. Amarante   +6 more
semanticscholar   +1 more source

Transcriptome analysis unraveled potential mechanisms of resistance to Haemonchus contortus infection in Merino sheep populations bred for parasite resistance

Veterinary Research, 2019
Haemonchus contortus is one of the most pathogenic gastrointestinal nematodes in small ruminants. To understand molecular mechanisms underlying host resistance to this parasite, we used RNA-sequencing technology to compare the transcriptomic response of ...
Runfeng Zhang, Fang Liu, P. Hunt, Congjun Li, Lichun Zhang, A. Ingham, Robert W. Li   +6 more
semanticscholar   +1 more source

Bio-guided fractionation to identify Senegalia gaumeri leaf extract compounds with anthelmintic activity against Haemonchus contortus eggs and larvae.

Veterinary parasitology, 2019
Small ruminants browsing in tropical forests readily consume the foliage of Senegalia gaumeri. A S. gaumeri methanol:water extract was recently shown to have ovicidal activity against Haemonchus contortus eggs in vitro. In the present study, the fraction
G. Castañeda-Ramírez, J. Torres-Acosta, Carlos Alfredo Sandoval-Castro, R. Borges-Argáez, M. Cáceres-Farfán, Gabriela Mancilla-Montelongo, C. Mathieu   +6 more
semanticscholar   +1 more source

Efficiency of the Bioverm® (Duddingtonia flagrans) fungal formulation to control in vivo and in vitro of Haemonchus contortus and Strongyloides papillosus in sheep

3 Biotech, 2020
F. R. Braga, C. M. Ferraz, E. N. da Silva, J. V. de Araújo   +3 more
semanticscholar   +1 more source

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ABC-transporter gene expression in ivermectin-susceptible and resistant Haemonchus contortus isolates.

Veterinary parasitology, 2022
Mammalian efflux transporters of the ATP-binding cassette (ABC) regulate cellular levels of endo- and xenobiotics by transporting molecules across cell membranes and are involved in diverse biological processes.
L. Maté, M. Ballent, C. Cantón, C. Lanusse, L. Ceballos, L. Alvarez L, Juan Pedro Lirón   +6 more
semanticscholar   +1 more source

Biological control of sheep nematode Haemonchus contortus using edible mushrooms

, 2021
This study evaluated in vitro the morphology of ten strains of edible mushroom: Pleurotus ostreatus (strains 1123 and 0152), P. eryngii (strains 1290 and 1291), P. cornucopiae (strains 1328 and 1330), Coprinus comatus (strain 1103), Panus sp. (strain 801)
R. Comans-Pérez, J. Sánchez, L. Al-Ani, M. González-Cortázar, G. Castañeda-Ramírez, P. M. Gives, Alma Delia Sánchez-García, Jair Millán-Orozco, L. Aguilar-Marcelino   +8 more
semanticscholar   +1 more source