Results 201 to 210 of about 22,562,840 (346)

Halfspace Depth

open access: yesWIREs Computational Statistics, Volume 17, Issue 3, September 2025.
The halfspace depth generalizes quantiles to multivariate data. This is a bagplot—a depth‐based analog of a boxplot. It succinctly captures the geometry of the bivariate dataset (blue/red points) and identifies the four red points in the top left corner as deviating from the general pattern of the data.
Stanislav Nagy
wiley   +1 more source

Impact of Model‐Informed Drug Development on Drug Development Cycle Times and Clinical Trial Cost

open access: yesClinical Pharmacology &Therapeutics, Volume 118, Issue 2, Page 378-385, August 2025.
Model‐informed drug development (MIDD) integrates data to quantify benefit/risk informing objective drug discovery and development decisions. An additional critical benefit of MIDD is postulated to be improvement in trial and program efficiencies. While the application of MIDD has grown, there have been no clear examples across programs to demonstrate ...
Vaishali Sahasrabudhe   +4 more
wiley   +1 more source

AIDS and haemophilia: morbidity and morality in a well defined population. [PDF]

open access: bronze, 1985
P. Jones   +7 more
openalex   +1 more source

Patterns of Direct Oral Anticoagulant Use in Pediatric Patients: Results From a Multicenter National Database

open access: yesPediatric Blood &Cancer, Volume 72, Issue 8, August 2025.
ABSTRACT Background Direct oral anticoagulants (DOACs) have quickly gained favor due to oral availability, favorable risk profile, and reduced lab monitoring. This study aims to evaluate trends in DOAC use among pediatric patients with new venous thrombotic events (VTE) and factors associated with their selection.
Molly Mack   +2 more
wiley   +1 more source

Immunological abnormalities in haemophilia: are they caused by American factor VIII concentrate? [PDF]

open access: bronze, 1983
KarinS. Froebel   +5 more
openalex   +1 more source

Treatment of bleeding episodes in haemophilia A complicated by a factor VIII inhibitor in patients receiving Emicizumab. Interim guidance from UKHCDO Inhibitor Working Party and Executive Committee

open access: yesHaemophilia, 2018
P. Collins   +10 more
semanticscholar   +1 more source

Association Between Hair Cortisol and Psychopathology in Children With a Chronic Physical Illness

open access: yesStress and Health, Volume 41, Issue 4, August 2025.
ABSTRACT Children with a chronic physical illness (CPI) experience significant stress and are at a greater risk of psychopathology. However, little is known about chronic stress and its relationship with psychopathology in this population. Over the last decade, hair cortisol concentration (HCC) has emerged as a viable biomarker of chronic stress.
Emma A. L. Littler   +3 more
wiley   +1 more source

HAEMATURIA IN PATIENTS WITH HAEMOPHILIA

open access: yesZdravniški Vestnik, 2008
BACKGROUND A review article intends to discover a cause, frequency, treatment and complications ofhaematuria in patients with haemophilia. METHODS A review of PubMed (1969–2007) for key words haemophilia, haematuria and renaldisease. RESULTS Four studies
Majda Benedik Dolničar
doaj  

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