Results 201 to 210 of about 22,562,840 (346)
The halfspace depth generalizes quantiles to multivariate data. This is a bagplot—a depth‐based analog of a boxplot. It succinctly captures the geometry of the bivariate dataset (blue/red points) and identifies the four red points in the top left corner as deviating from the general pattern of the data.
Stanislav Nagy
wiley +1 more source
Impact of Model‐Informed Drug Development on Drug Development Cycle Times and Clinical Trial Cost
Model‐informed drug development (MIDD) integrates data to quantify benefit/risk informing objective drug discovery and development decisions. An additional critical benefit of MIDD is postulated to be improvement in trial and program efficiencies. While the application of MIDD has grown, there have been no clear examples across programs to demonstrate ...
Vaishali Sahasrabudhe+4 more
wiley +1 more source
AIDS and haemophilia: morbidity and morality in a well defined population. [PDF]
P. Jones+7 more
openalex +1 more source
ABSTRACT Background Direct oral anticoagulants (DOACs) have quickly gained favor due to oral availability, favorable risk profile, and reduced lab monitoring. This study aims to evaluate trends in DOAC use among pediatric patients with new venous thrombotic events (VTE) and factors associated with their selection.
Molly Mack+2 more
wiley +1 more source
Immunological abnormalities in haemophilia: are they caused by American factor VIII concentrate? [PDF]
KarinS. Froebel+5 more
openalex +1 more source
Association Between Hair Cortisol and Psychopathology in Children With a Chronic Physical Illness
ABSTRACT Children with a chronic physical illness (CPI) experience significant stress and are at a greater risk of psychopathology. However, little is known about chronic stress and its relationship with psychopathology in this population. Over the last decade, hair cortisol concentration (HCC) has emerged as a viable biomarker of chronic stress.
Emma A. L. Littler+3 more
wiley +1 more source
HAEMATURIA IN PATIENTS WITH HAEMOPHILIA
BACKGROUND A review article intends to discover a cause, frequency, treatment and complications ofhaematuria in patients with haemophilia. METHODS A review of PubMed (1969–2007) for key words haemophilia, haematuria and renaldisease. RESULTS Four studies
Majda Benedik Dolničar
doaj
(2) PATHOLOGIC PHYSIOLOGY OF HAEMOPHILIA AND RELATED DISEASES
Sotoharu YAMADA
openalex +2 more sources