Results 251 to 260 of about 12,413,959 (307)

Haemophilia A and Haemophilia B

2019
WOS ...
Carlos Rodriguez-Merchan, E., Hoots, Keith, Tuddenham, Edward, Ragni, Margaret, Hedner, Ulla, DiMichele, Donna M., Lusher, Jeanne, Konkle, Barbara, Brand, Brigit, Escobar, Miguel A., Ingerslev, Jorgen, Kessler, Craig M., Marbet, German A., Schulman, Sam, Marder, Victor, Beeton, Karen, Abshire, Tom, Kulkarni, Roshni, Preston, Francis E., Kavakli, Kaan, Berntorp, Erik   +20 more
openaire   +1 more source

[Haemophilia A and haemophilia B. Are there relevant clinical differences?].

Hamostaseologie, 2010
Haemophilia B (HB) was described in 1952 as a single disease for the first time. In comparison to haemophilia A (HA) the bleeding tendency seemed to be less severe. The aim of this study was to investigate this hypothesis in all patients with HA and HB treated in the haemophilia care center of the Vivantes Klinikum.All patients with severe HA and HB ...
R, Klamroth, M, Orlovic, C, Kubicek-Hofman, S, Gottstein   +3 more
openaire   +2 more sources

Subperiosteal Haemorrhage in Haemophilia A and B

Acta Paediatrica, 1961
SummaryDescription of two cases of extensive subperiosteal haematoma of the heel in a patient with haemophilia A and in a patient with haemophilia B. These haema‐tomata gave rise to extensive destruction of the calcaneus. Discussion of the means by which recovery was obtained.We are grateful to Dr. H. A. E.
, van CREVELD, M J, KINGMA
openaire   +2 more sources

Haemophilia A and B

2012
Haemophilia A and B are hereditary, X-linked bleeding disorders caused, respectively, by deficiencies of coagulation factors FVIII and FIX. Haemophilia is among the most common hereditary human disorders; both haemophilia A and B have been identified in domestic animals and, as in humans, haemophilia A is the most common form.
openaire   +1 more source

The molecular basis of haemophilia B

Haemophilia, 1998
Summary. The cloning and isolation of the human factor VIII (FVIII) gene in the mid‐1980s has lead to 10 years of increasing understanding of the genetic and hence the molecular basis of haemophilia A. These studies are not only of enormous potential benefit for accurate carrier detection and prenatal diagnosis in families with haemophilia A, but ...
C. A. Lee, C. M. Kessler, D. Varon, U. Martinowitz, M. Heim, IAN PEAKE   +5 more
openaire   +3 more sources

Haemophilia B: current pharmacotherapy and future directions

Expert Opinion on Pharmacotherapy, 2012
Hemophilia B is a rare hereditary hemorrhagic disorder characterized by deficiency of the clotting factor IX (FIX). Hemophilia B patients experience mild to severe bleeding complications according to the degree of FIX defect. Nowadays, the most challenging complication of individuals with hemophilia B is the development of alloantibodies, which render ...
Massimo, Franchini, Francesco, Frattini, Silvia, Crestani, Carlo, Bonfanti   +3 more
openaire   +2 more sources

Another Genetic Variant of Haemophilia B: Haemophilia B Leyden

Scandinavian Journal of Haematology, 1970
J J, Veltkamp, J, Meilof, H G, Remmelts, D, van der Vlerk, E A, Loeliger   +4 more
openaire   +2 more sources

Eftrenonacog Alfa: A Review in Haemophilia B

Drugs, 2017
Eftrenonacog alfa (Alprolix™) is a recombinant fusion protein comprising human factor IX (FIX) covalently linked to the constant region (Fc) domain of human IgG1 (i.e. rFIXFc). The presence of the Fc domain extends the terminal half-life (t½) of rFIXFc, permitting prolonged treatment intervals.
openaire   +2 more sources

CpG POLYMORPHISMS AND HAEMOPHILIA B

The Lancet, 1989
MichaelW. Gray, P.R. Winship
openaire   +2 more sources

Haemophilia

Nature Reviews Disease Primers, 2021
Erik Berntorp, Kathelijn Fischer, Daniel P Hart   +2 more
exaly