Results 1 to 10 of about 2,365 (163)

Epidemiology of Haemophilus ducreyi Infections [PDF]

Emerging Infectious Diseases, 2016
The global epidemiology of Haemophilus ducreyi infections is poorly documented because of difficulties in confirming microbiological diagnoses. We evaluated published data on the proportion of genital and nongenital skin ulcers caused by H.
Camila González-Beiras, Michael Marks, Cheng Y. Chen, Sally Roberts, Oriol Mitjà   +4 more
doaj   +7 more sources

Endemic infectious cutaneous ulcers syndrome in the Oti Region of Ghana: Study of cutaneous leishmaniasis, yaws and Haemophilus ducreyi cutaneous ulcers. [PDF]

PLoS ONE, 2023
BackgroundA recent study detected cutaneous leishmaniasis (CL) in 31.9% of persons with skin ulcers in the Oti Region of Ghana, resulting in a need to investigate other potential causes of the unexplained skin ulcers.Methodology/principal findingsA ...
Richard Adjei Akuffo, Carmen Sanchez, Ivy Amanor, Jennifer Seyram Amedior, Nana Konama Kotey, Francis Anto, Thomas Azurago, Anthony Ablordey, Felicia Owusu-Antwi, Abate Beshah, Yaw Ampem Amoako, Richard Odame Phillips, Michael Wilson, Kingsley Asiedu, Jose-Antonio Ruiz-Postigo, Javier Moreno, Mourad Mokni   +16 more
doaj   +2 more sources

Multiplex Mediator Displacement Loop-Mediated Isothermal Amplification for Detection of Treponema pallidum and Haemophilus ducreyi [PDF]

Emerging Infectious Diseases, 2020
Yaws, a neglected tropical disease caused by the bacterium Treponema pallidum subspecies pertenue, manifests as ulcerative skin lesions. Nucleic acid amplification tests, like loop-mediated isothermal amplification (LAMP), are versatile tools to ...
Lisa Becherer, Sascha Knauf, Michael Marks, Simone Lueert, Sieghard Frischmann, Nadine Borst, Felix von Stetten, Sibauk Bieb, Yaw Adu-Sarkodie, Kingsley Asiedu, Oriol Mitjà, Mohammed Bakheit   +11 more
doaj   +2 more sources

Haemophilus ducreyi Infection Induces Oxidative Stress, Central Metabolic Changes, and a Mixed Pro- and Anti-inflammatory Environment in the Human Host [PDF]

mBio, 2022
Few studies have investigated host-bacterial interactions at sites of infection in humans using transcriptomics and metabolomics. Haemophilus ducreyi causes cutaneous ulcers in children and the genital ulcer disease chancroid in adults.
Julie A. Brothwell, Kate R. Fortney, Hongyu Gao, Landon S. Wilson, Caroline F. Andrews, Tuan M. Tran, Xin Hu, Teresa A. Batteiger, Stephen Barnes, Yunlong Liu, Stanley M. Spinola   +10 more
doaj   +2 more sources

Interactions of the Skin Pathogen Haemophilus ducreyi With the Human Host [PDF]

Frontiers in Immunology, 2021
The obligate human pathogen Haemophilus ducreyi causes both cutaneous ulcers in children and sexually transmitted genital ulcers (chancroid) in adults. Pathogenesis is dependent on avoiding phagocytosis and exploiting the suppurative granuloma-like niche,
Julie A. Brothwell, Brad Griesenauer, Li Chen, Stanley M. Spinola, Stanley M. Spinola, Stanley M. Spinola   +5 more
doaj   +2 more sources

Direct Whole-Genome Sequencing of Cutaneous Strains of Haemophilus ducreyi [PDF]

Emerging Infectious Diseases, 2018
Haemophilus ducreyi, which causes chancroid, has emerged as a cause of pediatric skin disease. Isolation of H. ducreyi in low-income settings is challenging, limiting phylogenetic investigation.
Michael Marks, Maria Fookes, Josef Wagner, Rosanna Ghinai, Oliver Sokana, Yaw-Adu Sarkodie, Anthony W. Solomon, David C.W. Mabey, Nicholas R. Thomson   +8 more
doaj   +2 more sources

Prevalence and risk factors associated with Haemophilus ducreyi cutaneous ulcers in Cameroon. [PDF]

PLoS Neglected Tropical Diseases, 2023
Epidemics of yaws-like cutaneous ulcers are regularly documented in children in the tropics. They occur mainly in poor and remote communities without access to health facilities.
Philippe Ndzomo, Serges Tchatchouang, Earnest Njih Tabah, Theophilus Njamnshi, Mireille Victorine Noah Tsanga, Jude Alexis Bondi, Rebecca Handley, Camila González Beiras, Jules Tchatchueng, Claudia Müller, Simone Lüert, Sascha Knauf, Onana Boyomo, Emma Harding-Esch, Oriol Mitja, Tania Crucitti, Michael Marks, Sara Eyangoh   +17 more
doaj   +2 more sources

Multiplex Recombinase Polymerase Amplification Assay for Simultaneous Detection of Treponema pallidum and Haemophilus ducreyi in Yaws-Like Lesions [PDF]

Tropical Medicine and Infectious Disease, 2020
Yaws is a skin debilitating disease caused by Treponema pallidum subspecies pertenue with most cases reported in children. World Health Organization (WHO) aims at total eradication of this disease through mass treatment of suspected cases followed by an ...
Michael Frimpong, Shirley Victoria Simpson, Hubert Senanu Ahor, Abigail Agbanyo, Solomon Gyabaah, Bernadette Agbavor, Ivy Brago Amanor, Kennedy Kwasi Addo, Susanne Böhlken-Fascher, Jonas Kissenkötter, Ahmed Abd El Wahed, Richard Odame Phillips   +11 more
doaj   +2 more sources

Transmission of viable Haemophilus ducreyi by Musca domestica. [PDF]

PLoS Neglected Tropical Diseases
Haemophilus ducreyi was historically known as the causative agent of chancroid, a sexually-transmitted disease causing painful genital ulcers endemic in many low/middle-income nations.
Haley D Stabile, Kayla McCandless, Rachel A Donlan, Jordan R Gaston, Tricia L Humphreys   +4 more
doaj   +2 more sources

The protein degradation system encoded by hslUV (ClpYQ) is dispensable for the virulence of Haemophilus ducreyi in human volunteers [PDF]

Infection and Immunity
Haemophilus ducreyi causes cutaneous ulcers in children who live in yaws-endemic countries and the genital ulcer disease chancroid. In the human host, H. ducreyi resides in an abscess and may need to resist both heat and oxidative stress, which result in
Kate R. Fortney, Julie A. Brothwell, Teresa A. Batteiger, Rory Duplantier, Barry P. Katz, Stanley M. Spinola   +5 more
doaj   +2 more sources