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Haemophilus ducreyi adheres to human keratinocytes
Microbial Pathogenesis, 1994Haemophilus ducreyi, Moraxella catarrhalis and a non-piliated Escherichia coli K-12 strain were studied for their ability to bind to human keratinocytes in vitro. Epidermal cells isolated from neonatal foreskins were grown to confluence in serum-free keratinocyte media.
R J, Brentjens +2 more
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Isolation and cultivation of Haemophilus ducreyi
Journal of Clinical Microbiology, 1982A useful method for isolating and recognizing Haemophilus ducreyi from chancres and buboes of male patients is presented. A total of 41 clinical isolates of H. ducreyi were recovered from 33 patients over an 8-year period, and the experience with the 15 most recent isolates is presented in detail.
T R, Oberhofer, A E, Back
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Haemophilus ducreyi Detection by PCR
2003Genital ulcers are typically caused by one of three organisms, Haemophilus ducreyi, Treponema pallidum, or herpes simplex virus, which cause chancroid, syphilis, and genital herpes, respectively. Although traditionally these diseases have been differentiated by their clinical presentation, there is considerable overlap in their clinical manifestations (
P A, Totten, J, Kuypers, S A, Morse
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Characteristics of Haemophilus ducreyi in culture
Journal of Clinical Microbiology, 1984Growth on different media and the influence of culture conditions were studied on 19 recently isolated strains of Haemophilus ducreyi, none of which had more than four passages on artificial media. The results were compared with 10 laboratory strains, which had an unknown number of passages in vitro. For all strains, growth was best on 30% rabbit blood
A W, Sturm, H C, Zanen
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Experimental Human Infection with Haemophilus ducreyi
The Journal of Infectious Diseases, 1994Four subjects were experimentally infected with Haemophilus ducreyi. Lesions developed only at sites where live bacteria were inoculated on abraded skin. No subject developed fever, lymphadenopathy, or disseminated infection during a 3-day observation period.
S M, Spinola +4 more
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Current Opinion in Infectious Diseases, 2016
This article provides an overview of the biology, epidemiology, clinical features, diagnostic tests, and treatment of Haemophilus ducreyi infection, with special reference to the decline of chancroid and the recent emergence of H. ducreyi as a pathogen responsible for chronic limb ulceration clinically similar to yaws.Chancroid has declined in ...
David A, Lewis, Oriol, Mitjà
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This article provides an overview of the biology, epidemiology, clinical features, diagnostic tests, and treatment of Haemophilus ducreyi infection, with special reference to the decline of chancroid and the recent emergence of H. ducreyi as a pathogen responsible for chronic limb ulceration clinically similar to yaws.Chancroid has declined in ...
David A, Lewis, Oriol, Mitjà
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Haemophilus ducreyi and chancroid
2010Haemophilus ducreyi is a Gram-negative, facultative anaerobic bacillus that is the cause of chancroid, which is endemic in sub-Saharan Africa and the Caribbean, although the overall global incidence of the condition has decreased dramatically since the mid 1990s.
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Neutrophil Degranulation Induced by Haemophilus ducreyi
bchm, 2001Haemophilus ducreyi is the causative bacterium of genital ulcers, which are collectively known as chancroid. Little is known about the cytotoxicity of H. ducreyi. The virulent strains are relatively resistant to phagocytosis and apoptosis by neutrophils.
B, Odhav, A, Hoosen, W, Sturm
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Haemophilus ducreyi: pathogenesis and protective immunity
Trends in Microbiology, 1995Haemophilus ducreyi is the etiological agent of chancroid, a sexually transmitted disease that is common in developing countries and that has characteristic genital mucocutaneous lesions. The adherence and growth of bacteria on the surface of eukaryotic cells, and the production of cytotoxin(s) result in cell damage that may be responsible for the ...
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