Mapping the distribution of yaws and Haemophilus ducreyi in the western north region of Ghana [PDF]
Background Treponema pallidum subspecies pertenue and Haemophilus ducreyi cause skin ulcers in impoverished communities. Historical serologic records from Ghana focus on T. pallidum, omitting potential H. ducreyi cases. The objective of this study was to
Shirley Victoria Simpson +11 more
doaj +2 more sources
Haemophilus ducreyi Associated with Skin Ulcers among Children, Solomon Islands [PDF]
During a survey of yaws prevalence in the Solomon Islands, we collected samples from skin ulcers of 41 children. Using PCR, we identified Haemophilus ducreyi infection in 13 (32%) children.
Michael Marks +8 more
doaj +2 more sources
A high-resolution view of the immune and stromal cell response to Haemophilus ducreyi infection in human volunteers [PDF]
Haemophilus ducreyi causes the genital ulcer disease chancroid and cutaneous ulcers in children. To study its pathogenesis, we developed a human challenge model in which we infect the skin on the upper arm of human volunteers with H.
Julie A. Brothwell +11 more
doaj +2 more sources
Haemophilus ducreyi cutaneous ulcer contracted at Seram Island, Indonesia, presented in the Netherlands. [PDF]
We describe the first case of a cutaneous ulcer caused by Haemophilus ducreyi imported from Indonesia to the Netherlands. Skin infections caused by H.
Jarne M van Hattem +6 more
doaj +2 more sources
Molecular phylogenetic analysis of non-sexually transmitted strains of Haemophilus ducreyi. [PDF]
Haemophilus ducreyi, the etiologic agent of chancroid, has been previously reported to show genetic variance in several key virulence factors, placing strains of the bacterium into two genetically distinct classes.
Jordan R Gaston +2 more
doaj +2 more sources
LAMP4yaws: Treponema pallidum, Haemophilus ducreyi loop mediated isothermal amplification − protocol for a cross-sectional, observational, diagnostic accuracy study [PDF]
Introduction Yaws, caused by the bacterium Treponema pallidum subsp. pertenue, is a neglected tropical disease targeted for eradication by 2030. Improved diagnostics will be essential to meet this goal.
Michael Marks +28 more
doaj +2 more sources
The Laboratory Diagnosis of Haemophilus ducreyi [PDF]
Chancroid is a sexually transmitted infection caused by Haemophilus ducreyi. This fastidious, Gram-negative coccobacilli dies rapidly outside the human host, making diagnostic testing using culture methods difficult.
Michelle Alfa
doaj +3 more sources
Functional Study of Haemophilus ducreyi Cytolethal Distending Toxin Subunit B [PDF]
The Cytolethal Distending Toxin (CDT) is produced by many Gram-negative pathogenic bacteria responsible for major foodborne diseases worldwide. CDT induces DNA damage and cell cycle arrest in host-cells, eventually leading to senescence or apoptosis ...
Benoît J. Pons +5 more
doaj +2 more sources
Detection of Haemophilus ducreyi from environmental and animal samples in Cameroon. [PDF]
BackgroundChildren in parts of Africa, the South Pacific, and Southeast Asia frequently develop cutaneous ulcers caused by two bacteria: Haemophilus ducreyi (HD) and Treponema pallidum subspecies pertenue (causative agent of yaws).
Philippe Ndzomo +5 more
doaj +2 more sources
Haemophilus ducreyi Cutaneous Ulcer Strains Are Nearly Identical to Class I Genital Ulcer Strains. [PDF]
BackgroundAlthough cutaneous ulcers (CU) in the tropics is frequently attributed to Treponema pallidum subspecies pertenue, the causative agent of yaws, Haemophilus ducreyi has emerged as a major cause of CU in yaws-endemic regions of the South Pacific ...
Dharanesh Gangaiah +11 more
doaj +2 more sources

