Results 21 to 30 of about 2,365 (163)

Epidemiological Patterns of Genital Ulcer Disease and Human Immunodeficiency Virus Among Public Clinic Attendees in Mthatha, Eastern Cape, South Africa [PDF]

Diseases
Background: Sexually transmitted infections (STIs) are common globally, posing significant public health challenges and financial strain, especially in low- and middle-income countries.
Thembisa R. Tshaka, Lindiwe M. Faye, Teke R. Apalata, Zizipho Z. A. Mbulawa   +3 more
doaj   +2 more sources

Haemophilus ducreyi Cutaneous Ulcer Strains Diverged from Both Class I and Class II Genital Ulcer Strains: Implications for Epidemiological Studies. [PDF]

PLoS Neglected Tropical Diseases, 2016
BackgroundHaemophilus ducreyi has emerged as a major cause of cutaneous ulcers (CU) in yaws-endemic regions of the tropics in the South Pacific, South East Asia and Africa. H.
Dharanesh Gangaiah, Stanley M Spinola
doaj   +2 more sources

Nucleic Acid Amplification‐Based Technologies (NAAT)—Toward Accessible, Autonomous, and Mobile Diagnostics

Advanced Materials Technologies, Volume 8, Issue 20, October 24, 2023., 2023
This review highlights the current state‐of‐the‐art research on nucleic acid amplification‐based diagnostic technologies as well as commercial diagnostic products, discusses their performances, and emphasizes the role of academic‐industrial collaborations in developing the next generation of breakthrough technologies (i.e., more autonomous, affordable,
Vinayak Narasimhan, Hyunseo Kim, Seung Heon Lee, Hyukjoon Kang, Radwanul Hasan Siddique, Haeri Park, Yibing M. Wang, Hyuck Choo, Youngeun Kim, Shailabh Kumar   +9 more
wiley   +1 more source

Phosphoethanolamine Transferase LptA in Haemophilus ducreyi Modifies Lipid A and Contributes to Human Defensin Resistance In Vitro. [PDF]

PLoS ONE, 2015
Haemophilus ducreyi resists the cytotoxic effects of human antimicrobial peptides (APs), including α-defensins, β-defensins, and the cathelicidin LL-37.
Michael P Trombley, Deborah M B Post, Sherri D Rinker, Lorri M Reinders, Kate R Fortney, Beth W Zwickl, Diane M Janowicz, Fitsum M Baye, Barry P Katz, Stanley M Spinola, Margaret E Bauer   +10 more
doaj   +1 more source

The regulation of bacterial two‐partner secretion systems

Molecular Microbiology, Volume 120, Issue 2, Page 159-177, August 2023., 2023
Two‐partner secretion (TPS) systems play critical roles in bacterial pathogenesis by allowing the secretion of effector proteins such as cytolysins and adhesins. Here, we explore the diverse regulatory mechanisms that govern TPS system expression, including environmental stimuli, two‐component systems, quorum sensing, and global regulators, providing ...
Julian Trouillon, Ina Attrée, Sylvie Elsen   +2 more
wiley   +1 more source

Ulcerative skin lesions among children in Cameroon: It is not always Yaws.

PLoS Neglected Tropical Diseases, 2021
Outbreaks of yaws-like ulcerative skin lesions in children are frequently reported in tropical and sub-tropical countries. The origin of these lesions might be primarily traumatic or infectious; in the latter case, Treponema pallidum subspecies pertenue,
Jean-Philippe Ndzomo Ngono, Serges Tchatchouang, Mireille Victorine Noah Tsanga, Earnest Njih Tabah, Albert Tchualeu, Kingsley Asiedu, Lorenzo Giacani, Sara Eyangoh, Tania Crucitti   +8 more
doaj   +1 more source

Selective Exoenzymatic Labeling of Lipooligosaccharides of Neisseria gonorrhoeae with α2,6‐Sialoside Analogues

ChemBioChem, Volume 23, Issue 19, October 6, 2022., 2022
Selective exoenzymatic labeling (SEEL) can be applied as a glycoengineering technique for the modification of cell surface glycans on live bacteria; in this case the recombinant glycosyltransferase ST6Gal1 installed synthetic α2,6‐sialoside derivatives with a reporter group on the lipooligosaccharides of the bacterial pathogen Neisseria gonorrhoeae ...
Hanna de Jong, Maria J. Moure, Jet E. M. Hartman, Gerlof P. Bosman, Jun Yang Ong, Bart W. Bardoel, Geert‐Jan Boons, Marc M. S. M. Wösten, Tom Wennekes   +8 more
wiley   +1 more source

A Reference‐Scaled Average Bioequivalence Study of Azithromycin Tablets Manufactured in China and the United States: An Open‐Label, Randomized, Single‐Dose, 3‐Way Crossover Study in Healthy Chinese Subjects Under Fasted and Fed Conditions

Clinical Pharmacology in Drug Development, Volume 11, Issue 10, Page 1147-1156, October 2022., 2022
Abstract Azithromycin (Zithromax) is an azalide antibiotic that binds to the 50S ribosomal subunit of the susceptible organism and thereby interferes with its protein synthesis. An open‐label, randomized, single‐dose, 3‐way crossover bioequivalence study was conducted to compare the rate and extent of absorption of the azithromycin 250‐mg tablet ...
Beikang Ge, Cuiyun Li, Hua Wei, Yanhua Ding, Min Wu, Yuwang Liu, Kaiting Zhang, Ao Peng   +7 more
wiley   +1 more source

Genetic sequence data evidence that human faecal‐associated HF183 sequences are on human skin and in urine

Journal of Applied Microbiology, Volume 133, Issue 2, Page 232-240, August 2022., 2022
Abstract Aims The DNA marker HF183 is a partial 16S rRNA gene sequence highly specific to human‐associated Bacteroides including Bacteroides dorei. While HF183 is used to assess human faecal contamination in aquatic environments worldwide, little is known about the existence of HF183 and B.
Dong Li, Laurie C. Van De Werfhorst, Patricia A. Holden   +2 more
wiley   +1 more source

Virulence factors of Haemophilus ducreyi [PDF]

Infection and Immunity, 1984
We investigated the susceptibility of virulent and avirulent strains of Haemophilus ducreyi to the bactericidal activity of normal human serum and to phagocytosis and killing by human polymorphonuclear leukocytes (PMNL). Strains were defined as virulent if intradermal inoculation into a rabbit produced a typical necrotic lesion.
J A, Odumeru, G M, Wiseman, A R, Ronald
openaire   +2 more sources