Carriage of Haemophilus influenzae in the Pre- and Post-Hib Vaccine Eras Revisited: A Systematic Review and Meta-Analysis [PDF]
VaccinesBackground/Objectives: Re-emergence of Haemophilus influenzae serotype b (Hib) was reported in several European countries. We aimed to characterize the age distribution of H. influnezae carriage before and after Hib vaccination.
Samy Taha +3 more
doaj +2 more sources
Role of biofilm formation and antimicrobial resistance in urogenital Haemophilus influenzae isolates [PDF]
BMC MicrobiologyBackground Haemophilus influenzae (Hi) is increasingly detected in genital infections in humans and linked to septic abortion. We aimed to characterize 123 non-capsulated (non-typeable) Hi isolates from genital sites in women and investigate their ...
Nouria Belkacem +4 more
doaj +2 more sources
Analysis of Haemophilus species in patients with respiratory tract infections in Yaoundé, Cameroon
International Journal of Infectious Diseases, 2020 Objectives: To identifyHaemophilus species and characterise the antimicrobial susceptibility of isolates from patients with respiratory tract infections (RTIs) in Cameroon.
Serges Tchatchouang +2 more
exaly +3 more sources
Multi-Antigen Protein Vaccine Confers Protection in a Murine Model Against Intranasal Haemophilus influenzae Challenge [PDF]
VaccinesBackground: Non-typeable Haemophilus influenzae (NTHi) is a major cause of acute respiratory tract infections and chronic airway disease, despite its clinical importance, no licensed vaccine is available, largely due to the extensive genetic and ...
Nouria Belkacem +2 more
doaj +2 more sources
Resurgence of invasive Haemophilus influenzae type b disease in France, 2017–2024: epidemiological, genomic, and immunological insights [PDF]
npj VaccinesHaemophilus influenzae type b (Hib) conjugate vaccines have markedly reduced global invasive Hib disease. However, surveillance in France has shown a resurgence of Hib infections in children despite >90% vaccination coverage, coinciding with the shift ...
Nouria Belkacem +8 more
doaj +2 more sources
Haemophilus influenzaeInfections [PDF]
New England Journal of Medicine, 1972 Of the six typeable strains of this organism, type b is the most virulent, accounting for 95% of serious infections in children. Unexpectedly, in adults, nearly two thirds of isolates from blood and CSF were found to be nontypeable. The spectrum of clinical disease associated with type b and nontypeable strains is discussed.
J D, Connor, W L, Nyhan
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Haemophilus influenzae type b (Hib) seroprevalence in France: impact of vaccination schedules
BMC Infectious Diseases, 2021 Background Haemophilus influenzae serotype b (Hib) conjugate vaccine was introduced in France in 1992 as a 3 + 1 scheme at 2, 3, and 4 months (primary vaccination) with a booster at the age of 16–18 months. The vaccination was simplified in 2013 to a 2 +
Eva Hong +6 more
doaj +1 more source
npj Vaccines, 2022 Since January 2018, mandatory vaccination against meningococci serogroup C has been implemented in France for children
Samy Taha +2 more
doaj +1 more source
The rapid rebound of invasive meningococcal disease in France at the end of 2022
Journal of Infection and Public Health, 2023 Background: Invasive meningococcal disease (IMD) cases declined upon the implementation of non-pharmaceutical measures to control the COVID-19 pandemic. A rebound in IMD cases was feared upon easing these measures.
Samy Taha +6 more
doaj +1 more source
Product review on the IMD serogroup B vaccine Bexsero®
Human Vaccines & Immunotherapeutics, 2022 Bexsero® is a multicomponent vaccine composed of four major proteins of Neisseria meningitidis: the fHbp, NHBA, NadA and PorA. This vaccine was licensed against invasive meningococcal disease (IMD) due to serogroup B isolates.
Ala-Eddine Deghmane, Muhamed-Kheir Taha
doaj +1 more source