Results 51 to 60 of about 521,208 (170)

FMI-43 is a permeant blocker of mechanosensitive ion channels in sensory neurons and inhibits behavioural responses to mechanical stimuli [PDF]

, 2007
The molecular identity and pharmacological properties of mechanically gated ion channels in sensory neurons are poorly understood. We show that FM1-43, a styryl dye used to fluorescently label cell membranes, permeates mechanosensitive ion channels in ...
Wood John N, Wood, John, Drew, LJ, Drew, Liam, Liam J Drew, John N Wood, Wood, JN, Drew Liam J   +7 more
core   +1 more source

Porous Organic Polymers: From Molecular Design to Scalable Technologies

Small, Volume 22, Issue 46, 18 August 2026.
This review introduces porous organic polymers (POPs) for a wide range of applications, including energy storage, gas adsorption, catalysts, adsorbents, biomedical applications, sensors, and other exciting fields, and critically analyzes the synthesis and modification, and how structural topology influences the composites' architecture of POPs, along ...
Hossein Mashhadimoslem, Hadi Shayesteh, Simindokht Zarei‐Shokat, Rokhsareh Bakhtiari, Sheyda Abedi‐Banaei, Zahra Sheikhlouiharzand, Parnia Mohebimanesh, Seyed Mohammad Amin Ojagh, Bahareh Bakhtiari, Ali Maleki, Theo G. M. van de Ven, Sohrab Zendehboudi, Ali Elkamel   +12 more
wiley   +1 more source

Prolactin delays hair regrowth in mice [PDF]

, 2006
Mammalian hair growth is cyclic, with hair-producing follicles alternating between active (anagen) and quiescent (telogen) phases. The timing of hair cycles is advanced in prolactin receptor (PRLR) knockout mice, suggesting that prolactin has a role in ...
Ashby, M.G., Nixon, A.J., Pearson, A.J., Ormandy, C.J., Blazek, K., Wilkins, Richard J., Craven, A.J.   +6 more
core   +1 more source

Embedding Chemistry and Pharmacy Into Sustainability

Angewandte Chemie International Edition, Volume 65, Issue 29, 13 July 2026.
Chemistry and pharmacy provide products and processes that are indispensable for our high living standard. To understand their relationship with sustainability is important to allow them to contribute to sustainability in a sustainable manner. An integrated overview of green, circular, and sustainable chemistry and pharmacy is given and how they have t
Klaus Kümmerer
wiley   +1 more source

Characterizing human vestibular sensory epithelia for experimental studies: new hair bundles on old tissue and implications for therapeutic interventions in ageing. [PDF]

, 2015
Balance disequilibrium is a significant contributor to falls in the elderly. The most common cause of balance dysfunction is loss of sensory cells from the vestibular sensory epithelia of the inner ear.
Daniel J. Jagger, Axon, Patrick, Moffatt, D, Moffatt, David, Jagger, DJ, Tysome, James, Monksfield, Peter, Taylor, Ruth R., Jagger, Daniel J., Peter Monksfield, Donnelly, N, Lloyd, SK, Coulson, Chris, Irving, R, Coulson, C, Freeman, SR, Saeed, Shakeel R., Richard Irving, Simon K. Lloyd, Lloyd, Simon K., Forge, Andrew, Neil Donnelly, Freeman, Simon R., Shakeel R. Saeed, Taylor, RR, David Moffatt, Forge, A, Irving, Richard, Saeed, SR, Axon, P, Ruth R. Taylor, Monksfield, P, Simon R. Freeman, Donnelly, Neil, Chris Coulson, Tysome, J, Andrew Forge, Patrick Axon, James Tysome   +38 more
core   +1 more source

Zinc Exposure Causes Disulfidptosis to Induce Miscarriage by Up‐Regulating GATA1/METTL1/SLC7A11 Axis

Advanced Science, Volume 13, Issue 42, 28 July 2026.
Zn exposure up‐regulates GATA1, promoting GATA1‐mediated METTL1 and SLC7A11 transcription. It also enhances METTL1‐mediated m7G modification on SLC7A11 mRNA, increasing SLC7A11 mRNA stability. Ultimately, Zn exposure up‐regulates SLC7A11 at both transcriptional and post‐transcriptional levels, causing disulfidptosis. Knockdown of murine Slc7a11, Gata1,
Wenxin Huang, Yi Sun, Yanxin Wang, Haijun Yan, Xiaoping Yue, Weidong Wu, Xueyu Chen, Jinfang Zhang, Yanbing Lin, Qiong Lei, Nan Ji, Shuaishuai Xing, Liqin Zeng, Qingzheng Kang, Depeng Zhao, Geng Guo, Huidong Zhang   +16 more
wiley   +1 more source

Acute Toxicity by Hair Dye in Upper Egypt

, 2017
Hair-dye containing Para-phenylenediamine is widely used in Middle Eastern and some Asian countries. Many cases of toxicity and mortality either due to accidental or deliberate ingestion of hair dyes were reported. The aim of the present work is to study
Abdel-Moneim A
core   +1 more source

Principles of Food Safety and Toxicological Risk Assessment: Refining Hazards, Risk Management Communication, and Common Misconceptions

Comprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 4, July 2026.
ABSTRACT Toxicology has evolved into a robust scientific discipline since the 16th century when Paracelsus, the “Father of Toxicology,” established the basic yet fundamental principle that “the dose makes the poison.” Toxicology is often first associated with the chemical and pharmaceutical industries; however, it plays an equally relevant role in ...
Kenneth S. Rivera‐González, Jay S. Petrick, Christine M. Crincoli, Matthew D. Teegarden, Paul R. Hanlon   +4 more
wiley   +1 more source

Clinical presentation, treatment and outcome of paraphenylene-diamine induced acute kidney injury following hair dye poisoning: a cohort study [PDF]

, 2016
Introduction: in Africa and Asia hair dye is applied together with henna to decorate the hands and feet. Paraphenylene-diamine (PPD), a highly toxic constituent of hair dye can lead to acute kidney injury (AKI).
Taha, El Shafie, Mohammed, Osama, Ibrahim, Mohammed, Shigidi, Mazin   +3 more
core  

Long-term exposure to methylmercury and psychiatric symptoms in residents of Minamata, Japan [PDF]

, 2011
Introduction: It is well-known that prenatal or postnatal exposure to methylmercury can produce neurological signs in adults and children, exemplified by a case of large-scale poisoning in Minamata, Japan, in the 1950s.
Harada, Masazumi, Takashi Yorifuji, Inoue, Sachiko, Soshi Takao, Sachiko Inoue, Tsuda, Toshihide, Masazumi Harada, Yorifuji, Takashi, Toshihide Tsuda, Takao, Soshi   +9 more
core   +1 more source