Results 161 to 170 of about 1,862,657 (332)
Genetic Diagnosis and Discovery Enabled by Large Language Models
Advanced Science, EarlyView.We demonstrate that large language models (LLMs) can facilitate genetic diagnosis and discovery. LLMs were used to solve four types of genetic problems of sequentially increased complexity. An LLM‐based pipeline could analyze genetic variants in the genomic sequences of human hearing loss or rare genetic disease patients and assist in identifying ...
Tao Tu +25 more
wiley +1 more source
Effect of Scalp Position on Tensile Properties of Single Hair Fibers.
Int J Trichology, 2018 Kunchi C, Venkateshan KC, Adusumalli RB.
europepmc +1 more source
Advanced Science, EarlyView.Cell‐sized high‐frequency ultrasound using a lithium niobate transducer, previously ignored in reactive oxygen species (ROS) production, generated intracellular ROS at frequencies higher than conventionally used. The intracellular generation of ROS by cell‐sized high‐frequency ultrasound revealed in this study is expected to be applied to innovative ...
Kotaro Fujishiro +4 more
wiley +1 more source
Afro-textured hair care: a narrative review and recommendations for dermatologists. [PDF]
Int J Womens DermatolHumphrey JG +4 more
europepmc +1 more source
Advanced Science, EarlyView.This review outlines the wound healing process and factors influencing scar formation, explores how certain animals and human fetuses achieve scarless skin or tissue regeneration, and details tissue engineering material strategies employed in scarless wound dressings.
Meimei Fu +7 more
wiley +1 more source
Advanced Science, EarlyView.Functional compensation between clarin‐1 and clarin‐2 in cochlear hair cells. Hearing loss associated with CLRN1 mutations shows striking phenotypic variability; however, the underlying mechanisms remain poorly understood. This study reveals that clarin‐1 and clarin‐2 function cooperatively in cochlear hair cells to sustain mechanoelectrical ...
Maureen Wentling +17 more
wiley +1 more source
Relations between auditory brainstem response and threshold metrics in normal and impaired hearing listeners [PDF]
, 2015 Ernst, Frauke +3 more
core +1 more source
Advanced Science, EarlyView.This study identifies the cockroach‐derived peptide leucokinin VIII as a potent accelerator of diabetic wound healing. By activating the FAK‐ACTG1 axis, the peptide drives keratinocyte migration and filopodia formation. Delivered via a developed PLGA‐PEG‐PLGA thermosensitive hydrogel for sustained release, this approach significantly hastens wound ...
Zhengshan Qin +11 more
wiley +1 more source
Scanning Electron Microscopy and X-ray Microanalysis of Reconstructive Hair Fibers.
Int J Trichology, 2017 Combalia A +3 more
europepmc +1 more source
Development‐based In Vivo Bioreactor Strategy for Challenging Senescent Bone Reconstruction
Advanced Science, EarlyView.We present a development‐based in vivo bioreactor strategy to generate rejuvenated bone grafts (vBR‐Bone) within aged hosts. By enclosing vBR‐Bone fragments within an asymmetric biomimetic periosteum, segmental femoral defects in aged mice were successfully repaired within 6 weeks. Mechanistically, the multifactors of vBR‐Bone reconstitute a remodeling
Wenchao Zhang +9 more
wiley +1 more source