Results 181 to 190 of about 97,515 (304)

Genetic Diagnosis and Discovery Enabled by Large Language Models

Advanced Science, EarlyView.
We demonstrate that large language models (LLMs) can facilitate genetic diagnosis and discovery. LLMs were used to solve four types of genetic problems of sequentially increased complexity. An LLM‐based pipeline could analyze genetic variants in the genomic sequences of human hearing loss or rare genetic disease patients and assist in identifying ...
Tao Tu, Khaled Saab, Weida Liu, Zhouqing Fang, Zhuanfen Cheng, Svetolik Spasic, Maja Djurisic, Hiroaki Mohri, Wenlong Ren, Anil Palepu, Juraj Gottweis, Alan Karthikesalingam, Kavita Kulkarni, Annalisa Pawlosky, Devon Bonner, Elijah Kravets, Shruti Marwaha, Hector R. Mendez, Matthew T. Wheeler, Jonathan A. Bernstein, Undiagnosed Diseases Network, Cheng‐Yu Tsai, Chen‐Chi Wu, Konstantina M. Stankovic, Vivek Natarajan, Gary Peltz   +25 more
wiley   +1 more source

When Microneedling Backfires: A Hidden Risk of Hair Shaft Fragility in AGA Patients. [PDF]

J Cosmet Dermatol
Xu W, Luo J, Dai Y.
europepmc   +1 more source

An Intelligent Magneto‐Mechanical Platform for Cellular Sensing in 3D Microenvironments

Advanced Science, EarlyView.
This study presents MagMI, a pioneering machine intelligence‐driven magneto‐mechanical sensing platform. It utilizes magneto‐mechanical arrays and machine learning to achieve label‐free, real‐time monitoring and classification of cellular proliferation dynamics within 3D microenvironments.
Yue Quan, Yuxin Wang, Sen Ding, Bingpu Zhou, Yinning Zhou   +4 more
wiley   +1 more source

The heart of the hair fiber: How the inner structure of the coat reflects adaptive variation across color, sex, age, and body region in dromedary camels (<i>Camelus dromedarius</i>). [PDF]

Vet Anim Sci
Iglesias Pastrana C, Quispe Peña EC, Ciani E, Cisneros Rodríguez N, Delgado Bermejo JV, Camacho Vallejo ME.   +5 more
europepmc   +1 more source

A Microfiber‐Reinforced Janus Hydrogel E‐Skin With Recyclable Feature for Multimodal Sensing and Gender‐Specific Physiological Monitoring

Advanced Science, EarlyView.
Hydrogel‐based wearable electronics hold great promise for physiological monitoring in privacy‐sensitive regions. In this study, a polyurethane (PU) microfiber‐reinforced gelatin hydrogel e‐skin is developed, boasting multiple advantages such as ultra‐thinness, high toughness, and long‐term skin conformability.
Yarong Ding, Yufeng Li, Shaozhe Tan, Jiachun Sun, Xu Yang, Xuesi Zhang, Zhenhua Lin, Zhenyu Li, Yue Hao, Yannan Liu, Yingchun Li, Jingjing Chang   +11 more
wiley   +1 more source

Using Nanoindentation to Investigate the Effect of Manufacturing Pressure on the Microstructure and Stiffness of Pyrolytic Carbon [PDF]

, 2012
Landry, Nicholas
core   +1 more source

Construction of Skin‐Adaptable Slide‐Ring Hydrogels Based on Bile Acids Derived Polyrotaxanes for Smart Wound Dressing

Advanced Science, EarlyView.
A novel β‐cyclodextrin/bile acid‐based slide‐ring hydrogel was prepared via precise host–guest recognition and photopolymerization. This smart hydrogel dressing exhibited skin‐adaptive mechanical properties, pH‐responsive antibacterial activity, and integrated multi‐signal sensing (temperature, blood, and pressure) for advanced wound management ...
Wen Huang, Xueru Xiong, Qian Sun, Xiangting Lai, Lili Cai, Yunhua Chen, Lin Wang, Yong‐Guang Jia   +7 more
wiley   +1 more source

Evaluation of Human Hair Absorption and Retention. [PDF]

Clin Cosmet Investig Dermatol
Yun J, Kim SH, Yoo H, Park KH.
europepmc   +1 more source

Compensatory Interplay Between Clarin‐1 and Clarin‐2 Deafness‐Associated Proteins Governs Phenotypic Variability in Hearing

Advanced Science, EarlyView.
Functional compensation between clarin‐1 and clarin‐2 in cochlear hair cells. Hearing loss associated with CLRN1 mutations shows striking phenotypic variability; however, the underlying mechanisms remain poorly understood. This study reveals that clarin‐1 and clarin‐2 function cooperatively in cochlear hair cells to sustain mechanoelectrical ...
Maureen Wentling, Aïda Yakhlef Sanchez, Nicolas Thelen, Müge Senarisoy, Maria Hogg, Steven Condamine, Andrea Lelli, Emilia Wysocka, Pranav Patni, Sandrine Vitry, Kerem Yasin Yildizhan, Sébastien Le Gal, Sylvie Nouaille, Michael R. Bowl, Marc Thiry, Didier Dulon, Sedigheh Delmaghani, Aziz El‐Amraoui   +17 more
wiley   +1 more source

Hair-Like Flexible Airflow Sensor for Large-Area Airflow Sensing. [PDF]

Adv Sci (Weinh)
Xie Y, Liu F, Luo Y, Lin N, Wu X, Wu Z, Lu L.   +6 more
europepmc   +1 more source