Results 91 to 100 of about 47,932 (261)

Genotypes and Phenotypes of Patients With TSPEAR‐Related Disorder: Evidence of a Predominant Dental Phenotype

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT TSPEAR (chr. 21q22.3) encodes a protein involved in tooth development and is predominantly expressed in the enamel knot. Biallelic loss of function variants in TSPEAR cause ectodermal dysplasia, tooth agenesis and sensorineural hearing loss. However, the role of TSPEAR in auditory processes is unclear.
Debora Vergani   +17 more
wiley   +1 more source

253 Protective and cleansing effect of a skin care product against pollen allergen accumulation in the hair follicle [PDF]

open access: bronze, 2022
N. Lecland   +5 more
openalex   +1 more source

Genetic and Phenotypic Features of the Five Known Polyaminopathies: A Critical Narrative Review

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Polyaminopathies are a recently described family of rare genetic neurodevelopmental disorders. Polyaminopathies disrupt the biosynthesis of the primary polyamines: putrescine, spermidine, and spermine. Snyder–Robinson syndrome results from hemizygous loss‐of‐function variants in the spermine synthase (SMS) gene, resulting in decreased or ...
Elizabeth A. VanSickle   +26 more
wiley   +1 more source

Definition of critical skin defect and concepts of structural and functional repairs: Proposal and verification in a rat model

open access: yesAnimal Models and Experimental Medicine, EarlyView.
This graphical abstract illustrates the research process regarding skin defect repair using a rat model of skin defect. First, it assesses whether the barrier function of the skin is repaired. If the answer is “YES”, the study proceeds to focus on structural repair.
Cong Sun   +6 more
wiley   +1 more source

Confined B‐Cell Reconstruction and High T‐Cell Clonality Define Clinical Response to Cladribine Treatment

open access: yesAnnals of Neurology, EarlyView.
Cladribine tablets are approved for relapsing multiple sclerosis, mediating their clinical effect by moderately depleting lymphocytes. In a prospective, monocentric study including 22 patients completing 2 annual cycles of cladribine, B‐ and T‐cell receptor repertoires and relapse activity were assessed at baseline and after 24 months. T‐cell clonality
Tilman Schneider‐Hohendorf   +8 more
wiley   +1 more source

Advances and Challenges in Micro/Nanocarrier‐Based Dermal Drug Delivery Systems for Acne Treatment

open access: yesAdvanced NanoBiomed Research, EarlyView.
Topical acne treatment faces challenges from skin barriers and complex causes. Micro/nanocarriers improve drug delivery by enhancing bioavailability, targeting, and duration. Combining carriers creates synergistic effects for systematic intervention.
Jintao Yang   +7 more
wiley   +1 more source

Development and Characterization of Poly(Vinyl Alcohol)/Chitosan/Collagen Blends for the Treatment of Burn Wounds

open access: yesJournal of Applied Polymer Science, EarlyView.
Schematic illustration of the poly(vinyl alcohol)/chitosan/collagen blend, highlighting the main physicochemical characterization results and the biological evaluations performed in an in vivo burn model. ABSTRACT Burns are complex injuries that require effective and multifunctional therapeutic approaches.
Bruna V. Quevedo   +6 more
wiley   +1 more source

Structural and ultrastructural comparison of hair and feather follicles

open access: yesیافته‌های نوین در علوم زیستی, 2014
Formations of feather and hair follicles during embryonic stage are nearly similar. The aim of the present research is to study the similarities and differences between these two follicles in adult pigeons and rats. To fulfill this task, feather and hair
Ahmad Gharzi
doaj  

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