Results 51 to 60 of about 429,150 (378)

Bioengineering of Hair Follicle-like Structure for Validation of Hair Growth Promoting Compounds

Bioengineering, 2022
We aimed to establish screening and efficacy test techniques for use in the development of hair-promoting agents. To this end, we used the dermal papilla cell (DPc)-derived immortalized cell line (SV40T-hTERT DPc) and neonatal foreskin-derived ...
Hyun Woo Joo, Min Kyu Kim, Soon Sun Bak, Young Kwan Sung   +3 more
doaj   +1 more source

Live imaging of stem cell and progeny behaviour in physiological hair-follicle regeneration [PDF]

, 2012
Tissue development and regeneration depend on cell-cell interactions and signals that target stem cells and their immediate progeny. However, the cellular behaviours that lead to a properly regenerated tissue are not well understood.
A Uchugonova, Ann M. Haberman, C Lo Celso, CA Jahoda, David G. Gonzalez, E Fuchs, Elizabeth R. Deschene, FM Watt, G Cotsarelis, Giovanni Zito, H Oshima, H Ra, Ichiko Saotome, JB Wallingford, L Rubin, M Eiraku, M Petersson, M Rendl, MV Plikus, Panteleimon Rompolas, S Müller-Röver, SJ Morrison, SK Waghmare, T Tumbar, V Greco, V Greco, Valentina Greco, Y Xie, YV Zhang   +28 more
core   +1 more source

Comprehensive analysis of the circular RNA expression profile and circRNA–miRNA–mRNA network in the goat skin with divergent wool curvature

Animal Research and One Health, EarlyView., 2023
In our study, we conducted circRNA expression profiling of Zhongwei goat skin exhibiting divergent curvature wool phenotypes at two developmental stages using the RNA‐seq. Functional verification assay demonstrated that circRNA8782 regulated fibroblast proliferation.
Yingxiao Su, Zhanqiang Zhao, Zhanfa Liu, Xiaobo Li, Qian Chen, Yabin Pu, Lin Jiang, Xiaohong He, Yuehui Ma, Qianjun Zhao   +9 more
wiley   +1 more source

3D Numerical Simulation of Hair Formation Process Using a Particle Model [PDF]

, 2015
Hair is very important in determining human appearance. Although there are numerous observed data and experimental recordings for hair, a detailed mechanism of hair formation has not yet been elucidated.
Matsuoka Shogo, Morisaki Naoko, Nagayama Katsuya, Taguchi Hiroyuki   +3 more
core   +2 more sources

Pre-aggregation of scalp progenitor dermal and epidermal stem cells activates the WNT pathway and promotes hair follicle formation in in vitro and in vivo systems

Stem Cell Research & Therapy, 2019
Background Billions of dollars are invested annually by pharmaceutical companies in search of new options for treating hair loss conditions; nevertheless, the challenge remains.
Yiqun Su, Jie Wen, Junrong Zhu, Zhiwei Xie, Chang Liu, Chuan Ma, Qun Zhang, Xin Xu, Xunwei Wu   +8 more
doaj   +1 more source

Progress on mitochondria and hair follicle development in androgenetic alopecia: relationships and therapeutic perspectives. [PDF]

Stem Cell Res Ther
Hair loss has long been a significant concern for many individuals. Recent studies have indicated that mitochondria play a more crucial role in hair loss than previously recognized.
Dong TR, Li YJ, Jin SY, Yang FL, Xiong RX, Dai YQ, Song XZ, Guan CP.   +7 more
europepmc   +2 more sources

Gab1 and Mapk Signaling Are Essential in the Hair Cycle and Hair Follicle Stem Cell Quiescence [PDF]

, 2015
SummaryGab1 is a scaffold protein that acts downstream of receptor tyrosine kinases. Here, we produced conditional Gab1 mutant mice (by K14- and Krox20-cre) and show that Gab1 mediates crucial signals in the control of both the hair cycle and the self ...
Akilli Öztürk, Özlem, Birchmeier, Walter, Chmielowiec, Jolanta, Lan, Linxiang, Pakula, Hubert, Qi, Jingjing, Rajewsky, Klaus, Sasaki, Yoshiteru, Stein, Simone   +8 more
core   +3 more sources

Re-activation of Wnt/β-catenin Signaling Pathway in Hair Follicle Stem Cells in Treatment of Androgenetic Alopecia

Journal of Mazandaran University of Medical Sciences, 2022
Hair loss is a common hair disorder in human population. It affects quality of life and there are ongoing attempts to find permanent treatment for this condition. But, today there is no completely safe and protective treatment for all. Hair follicle stem
Razieh Zarei, Majid Saeedi, Ali Hosseinzade   +2 more
doaj  

Stem cell population asymmetry can reduce rate of replicative aging [PDF]

Journal of Theoretical Biology 331 (2013) 19-27, 2012
Cycling tissues such as the intestinal epithelium, germ line, and hair follicles, require a constant flux of differentiated cells. These tissues are maintained by a population of stem cells, which generate differentiated progenies and self-renew. Asymmetric division of each stem cell into one stem cell and one differentiated cell can accomplish both ...
arxiv   +1 more source

Self-organizing & stochastic behaviors during the regeneration of hair stem cells [PDF]

, 2011
Stem cells cycle through active and quiescent states. Large populations of stem cells in an organ may cycle randomly or in a coordinated manner. Although stem cell cycling within single hair follicles has been studied, less is known about regenerative ...
Andl, T, Baker, RE, Chen, CC, Chuong, CM, de la Cruz, D, Fare, C, Maini, Philip, Millar, SE, Plikus, MV, Widelitz, R   +9 more
core   +1 more source