Results 241 to 250 of about 30,614 (309)

Comprehensive Profiling of N6‐methyladnosine (m6A) Readouts Reveals Novel m6A Readers That Regulate Human Embryonic Stem Cell Differentiation

open access: yesAdvanced Science, EarlyView.
This research deciphers the m6A transcriptome by profiling its sites and functional readout effects: from mRNA stability, translation to alternative splicing, across five different cell types. Machine learning model identifies novel m6A‐binding proteins DDX6 and FXR2 and novel m6A reader proteins FUBP3 and L1TD1.
Zhou Huang   +11 more
wiley   +1 more source

Single‐Nucleus Multi‐Omics Reveals Hypoxia‐Driven Angiogenic Programs and Their Epigenetic Control in Sinonasal Squamous Cell Carcinoma

open access: yesAdvanced Science, EarlyView.
Single‐nucleus multi‐omics profiling of sinonasal squamous cell carcinoma unveils a hypoxia‐driven angiogenic axis. A specific hypoxic tumor subpopulation orchestrates endothelial tip cell differentiation via epigenetically regulated ADM and VEGFA secretion.
Chaelin You   +12 more
wiley   +1 more source

Functional, sustained recovery of hearing in Otoferlin-deficient mice using DB-OTO, a hair-cell-specific AAV-based gene therapy. [PDF]

open access: yesMol Ther Methods Clin Dev
Chung Y   +27 more
europepmc   +1 more source

Exosome-Based Therapies for Alopecia Areata: A Systematic Review of Clinical and Experimental Evidence. [PDF]

open access: yesInt J Mol Sci
Bulgaru-Iliescu AI   +6 more
europepmc   +1 more source

Black phosphorus nanosheets encapsulated microneedle for multifunctional therapy for androgenic alopecia. [PDF]

open access: yesJ Nanobiotechnology
Xiong S   +10 more
europepmc   +1 more source

Petrified child mummies by Paolo Gorini (19th century CE, Lodi, Lombardy, Italy): anthropological, pathological, and conservation perspectives. [PDF]

open access: yesFront Med (Lausanne)
Larentis O   +8 more
europepmc   +1 more source

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