Results 21 to 30 of about 30,614 (309)

Synchronization and chaos in systems of coupled inner-ear hair cells

open access: yesPhysical Review Research, 2021
Hair cells of the auditory and vestibular systems display astonishing sensitivity, frequency selectivity, and temporal resolution to external signals.
Justin Faber   +2 more
doaj   +1 more source

Evaluation of noninvasive biospecimens for transcriptome studies

open access: yesBMC Genomics, 2023
Transcriptome studies disentangle functional mechanisms of gene expression regulation and may elucidate the underlying biology of disease processes. However, the types of tissues currently collected typically assay a single post-mortem timepoint or are ...
Molly Martorella   +5 more
doaj   +1 more source

Cy3-ATP labeling of unfixed, permeabilized mouse hair cells

open access: yesScientific Reports, 2021
ATP-utilizing enzymes play key roles in hair bundles, the mechanically sensitive organelles of sensory hair cells in the inner ear. We used a fluorescent ATP analog, EDA-ATP-Cy3 (Cy3-ATP), to label ATP-binding proteins in two different preparations of ...
Itallia V. Pacentine   +1 more
doaj   +1 more source

Patch-clamp Recordings and Single Fiber Labeling from Spiral Ganglion Somata in Acutely Prepared Semi-intact Cochleae from Neonatal Rats

open access: yesBio-Protocol, 2022
Spiral ganglion neurons (SGN) are the primary neuronal pathway for transmitting sensory information from the inner ear to the brainstem. Recent studies have revealed significant biophysical and molecular diversity indicating that auditory neurons are ...
Alexander Markowitz   +2 more
doaj   +1 more source

Comparative studies of the specific activity of soft dosage forms minoxidil for trichological practice

open access: yesAktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2023
The treatment and prevention of hair loss have been a serious aesthetic problem for the population for a long time due to the widespread occurrence of the condition and its undesirable medical and social consequences.
V. V. Hladyshev   +6 more
doaj   +1 more source

Summing across different active zones can explain the quasi-linear Ca2+-dependencies of exocytosis by receptor cells

open access: yesFrontiers in Synaptic Neuroscience, 2010
Several recent studies of mature auditory and vestibular hair cells, and of visual and olfactory receptor cells, have observed nearly linear dependencies of the rate of neurotransmitter release events, or related measures, on the magnitude of Ca2+-entry ...
Peter Heil, Heinrich Neubauer
doaj   +1 more source

Cy3-RgIA-5727 Labels and Inhibits α9-Containing nAChRs of Cochlear Hair Cells

open access: yesFrontiers in Cellular Neuroscience, 2021
Efferent cholinergic neurons inhibit sensory hair cells of the vertebrate inner ear through the combined action of calcium-permeable α9α10-containing nicotinic acetylcholine receptors (nAChRs) and associated calcium-dependent potassium channels.
Fernando Fisher   +9 more
doaj   +1 more source

Unleashing the potential of the root hair cell as a single plant cell type model in root systems biology

open access: yesFrontiers in Plant Science, 2013
Plant root is an organ composed of multiple cell types with different functions. This multicellular complexity limits our understanding of root biology because –omics studies performed at the level of the entire root reflect the average responses of all ...
Zhenzhen eQiao, Marc eLibault
doaj   +1 more source

The Influence of Increasing Concentrations of AMPD on the Efficacy of Its Penetration into a Model Skin Sebum Layer

open access: yesPharmaceutics, 2020
Alcoholamines are widely used as auxiliary substances in various topical preparations. Their impact on the components of skin sebum allows them to be used in preparations that cleanse the skin of sebum in hair follicles.
Agnieszka Kostrzębska, Witold Musiał
doaj   +1 more source

Effects of different drying methods on smears of canine blood and effusion fluid [PDF]

open access: yesPeerJ, 2020
Background Glass slide preparations from a variety of specimens (blood, masses, effusions) are commonly made as part of the diagnostic work-up, however the effects of various drying methods in veterinary practice and diagnostic laboratory settings is not
Fiamma G. De Witte   +6 more
doaj   +2 more sources

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