Results 31 to 40 of about 2,575,346 (386)

The endocannabinoid/cannabinoid receptor 2 system protects against cisplatin-induced hearing loss [PDF]

open access: yes, 2018
Previous studies have demonstrated the presence of cannabinoid 2 receptor (CB2R) in the rat cochlea which was induced by cisplatin. In an organ of Corti-derived cell culture model, it was also shown that an agonist of the CB2R protected these cells ...
Asmita Dhukhwa   +8 more
core   +4 more sources

FM1-43 reveals membrane recycling in adult inner hair cells of the mammalian cochlea [PDF]

open access: yes, 2002
Neural transmission of complex sounds demands fast and sustained rates of synaptic release from the primary cochlear receptors, the inner hair cells (IHCs). The cells therefore require efficient membrane recycling.
Ashmore, JF   +2 more
core   +1 more source

Synchronization and chaos in systems of coupled inner-ear hair cells

open access: yesPhysical Review Research, 2021
Hair cells of the auditory and vestibular systems display astonishing sensitivity, frequency selectivity, and temporal resolution to external signals.
Justin Faber   +2 more
doaj   +1 more source

Fire in the Operating Room During Hypospadias Repair [PDF]

open access: yes, 2017
Fire in the operating room (OR) is a very distressful and shocking occurrence with potential dramatic consequences. Despite safety rules and rigorous recommendations, such unintentional events do occur every so often.
Boscarelli, Alessandro   +5 more
core   +2 more sources

Evaluation of noninvasive biospecimens for transcriptome studies

open access: yesBMC Genomics, 2023
Transcriptome studies disentangle functional mechanisms of gene expression regulation and may elucidate the underlying biology of disease processes. However, the types of tissues currently collected typically assay a single post-mortem timepoint or are ...
Molly Martorella   +5 more
doaj   +1 more source

Specific fluorescent labeling of chicken myofibril Z-line proteins catalyzed by guinea pig liver transglutaminase [PDF]

open access: yes, 1979
Guinea pig liver transglutaminase has been found to catalyze the covalent incorporation of dansylcadaverine into chicken skeletal muscle myofibril proteins.
Gard, David L., Lazarides, Elias
core   +1 more source

Developmental synaptic changes at the transient olivocochlear-inner hair cell synapse [PDF]

open access: yes, 2019
In the mature mammalian cochlea, inner hair cells (IHCs) are mainly innervated by afferent fibers that convey sound information to the CNS. During postnatal development, however, medial olivocochlear (MOC) efferent fibers transiently innervate the IHCs ...
Elgoyhen, Ana Belen   +5 more
core   +1 more source

Cy3-ATP labeling of unfixed, permeabilized mouse hair cells

open access: yesScientific Reports, 2021
ATP-utilizing enzymes play key roles in hair bundles, the mechanically sensitive organelles of sensory hair cells in the inner ear. We used a fluorescent ATP analog, EDA-ATP-Cy3 (Cy3-ATP), to label ATP-binding proteins in two different preparations of ...
Itallia V. Pacentine   +1 more
doaj   +1 more source

Comparative studies of the specific activity of soft dosage forms minoxidil for trichological practice

open access: yesAktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2023
The treatment and prevention of hair loss have been a serious aesthetic problem for the population for a long time due to the widespread occurrence of the condition and its undesirable medical and social consequences.
V. V. Hladyshev   +6 more
doaj   +1 more source

Patch-clamp Recordings and Single Fiber Labeling from Spiral Ganglion Somata in Acutely Prepared Semi-intact Cochleae from Neonatal Rats

open access: yesBio-Protocol, 2022
Spiral ganglion neurons (SGN) are the primary neuronal pathway for transmitting sensory information from the inner ear to the brainstem. Recent studies have revealed significant biophysical and molecular diversity indicating that auditory neurons are ...
Alexander Markowitz   +2 more
doaj   +1 more source

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