Results 51 to 60 of about 88,974 (304)

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Aspectos micromorfológicos da epiderme das brácteas em espécies de Scleria Berg. - Cyperaceae da Serra do Cipó

open access: yesRodriguésia
Resumo As microestruturas da epiderme foliar são consideradas de grande valor na taxonomia de vários grupos de Cyperaceae e a deposição da sílica é um dos aspectos considerados de maior relevância. Uma proporção variável das células epidérmicas apresenta
Vera Fatima Gomes Alves Pereira Lima   +1 more
doaj   +1 more source

From hair in India to hair India

open access: yesInternational Journal of Trichology, 2017
In all cultures, human hair and hairdo have been a powerful metaphor. Tracing back the importance and significance of human hair to the dawn of civilization on the Indian subcontinent, we find that all the Vedic gods are depicted as having uncut hair in mythological stories as well as in legendary pictures.
openaire   +4 more sources

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

The morphology of hairs in Verbascwn L. species

open access: yesActa Societatis Botanicorum Poloniae, 2014
The hairs on the flowers and perifloral leaves of 25 representatives of the genus Verbascum L. were examined. Thirteen morphological types of hairs were identified.
Barbara Grabias   +2 more
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Development, structure and evolutionary significance of seed appendages in Salix matsudana (Salicaceae). [PDF]

open access: yesPLoS ONE, 2018
The seeds of Salix and Populus (Salicaceae) are characterized by having numerous long hairs which loosely accompanying the seeds and a small annular appendage which surrounding the base of the seed along with tufted hairs.
Jianxia Li   +5 more
doaj   +1 more source

Orthotrichum pilosissimum (Orthotrichaceae), a new moss from arid areas of Nevada with unique axillary hairs

open access: yes, 2011
The stay was granted by the Spanish Ministry of Science and Innovation (FL) and the University of Valencia (RG). This work was funded by the Spanish Ministry of Education and Science, Grant CGL2007-61389.Orthotrichum pilosissimum is described from ...
Shevock, James   +9 more
core   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

open access: yesMolecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen   +19 more
wiley   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso   +5 more
wiley   +1 more source

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