Results 1 to 10 of about 22,262 (189)

Obinutuzumab combined with bendamustine for the treatment of hairy cell leukemia variant: a case report and literature review [PDF]

Frontiers in Oncology
Hairy cell leukemia variant (HCL-v) is a rare and more aggressive subtype of B-cell leukemia. While it shares certain clinical features with classical hairy cell leukemia (HCL-c), HCL-v typically follows a more malignant course and responds poorly to ...
Junjun Bai, Yi Zhang, Yi Zhang, Kangqi Lv, Bei Zhang, Hongxia Wang, Zhixin Pei, Yingxin Zhao, Jingjing Gu, Huimin Wu, Qinglin Song   +10 more
doaj   +2 more sources

Hairy Cell Leukemia

New England Journal of Medicine
Citation: 'hairy cell leukemia' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.13192 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms ...
Naing PT, Acharya U, Kumar A.
europepmc   +8 more sources

Pulmonary damage in a patient with hairy cell leukemia - infectious involvement or hematological disease activity? Case report

Biomedical Papers, 2023
Background. Hairy cell leukemia (HCL) is a rare indolent lymphoproliferative disease with an accumulation of mature B lymphocytes with fine reticular chromatin and cytoplasm with typical hairy-like cytoplasmic projections.
Dominika Ecsiova, Katerina Kamaradova, Marketa Nova, Petr Hoffmann, Petra Rozsivalova, Martin Simkovic, Pavel Zak   +6 more
doaj   +1 more source

Rare Lymphoid Malignancies of the Breast: A Report of Two Cases Illustrating Potential Diagnostic Pitfalls [PDF]

, 2012
Breast involvement by lymphoma is uncommon and poses challenges in diagnosis. Lymphomas may clinically, radiologically, and morphologically mimic both benign and neoplastic conditions.
Farkash, Evan Andrew, Ferry, Judith Ann, Harris, Nancy Lee, Hochberg, Ephraim Paul, Sohani, Aliyah, Takvorian, Ronald Wayne, Zuckerman, Dan S.   +6 more
core   +3 more sources

Case report: A case of classic hairy cell leukemia with CNS involvement treated with vemurafenib

Frontiers in Oncology, 2023
Hairy cell leukemia (HCL) is a rare mature B-cell lymphoproliferative disorder and most often presents as classic hairy cell leukemia. This entity is characterized by an indolent course and the presence of the BRAF V600E mutation.
Anna E. Johnson, Athul Raj Raju, Aasems Jacob, Gerhard C. Hildebrandt   +3 more
doaj   +1 more source

Cell-binding microarray application in diagnosis of hairy cell leukemia

Онкогематология, 2015
We describe an application of a cell-binding microarray – to parallel study of morphology, tartrate-resistant acid phosphatase activity and detection of surface markers on peripheral blood lymphocytes of 90  atients with suspected hairy cell leukemia ...
A. N. Khvastunova, L. S. Al-Radi, N. M. Kapranov, O. S. Fedyanina, L. A. Gorgidze, S. A. Lugovskaya, E. V. Naumova, U. L. Dzhulakyan, A. V. Filatov, F. I. Ataullakhanov, S. A. Kuznetsova   +10 more
doaj   +3 more sources

Bendamustine plus rituximab is an effective first-line treatment in hairy cell leukemia variant: A report of three cases [PDF]

, 2017
Hairy cell leukemia variant (HCLv) is a chronic lymphoproliferative disorder classified as a provisional entity in the 2016 WHO Classification of Lymphoid Tumors.
Berno, Tamara, Bertorelle, Roberta, Facco, Monica, Frezzato, Federica, Imbergamo, Silvia, Piazza, Francesco, Piva, Elisa, Pizzi, Marco, Riva, Marcello, Scomazzon, Edoardo, Semenzato, Gianpietro, Trentin, Livio, Visentin, Andrea   +12 more
core   +1 more source

HAIRY CELL LEUKEMIA

Medicine, 1978
Hairy cell leukemia is a chronic but steadily progressive malignancy usually of older males. Clinically, patients present with splenomegaly and/or cytopenia. The diagnosis is made by demonstration of the hairy cell in Wright's-stained peripheral blood and in bone marrow and by the characteristic histologic findings in the bone marrow biopsy and spleen ...
A, Turner, C R, Kjeldsberg
  +6 more sources

Constant activation of the RAF-MEK-ERK pathway as a diagnostic and therapeutic target in hairy cell leukemia

Haematologica, 2013
The BRAF-V600E mutation defines genetically hairy cell leukemia among B-cell leukemias and lymphomas. In solid tumors, BRAF-V600E is known to aberrantly activate the oncogenic MEK-ERK pathway, and targeted BRAF and/or MEK inhibitors have shown remarkable
Enrico Tiacci, Gianluca Schiavoni, Maria Paola Martelli, Emanuela Boveri, Roberta Pacini, Alessia Tabarrini, Silvia Zibellini, Alessia Santi, Valentina Pettirossi, Elisabetta Fortini, Stefano Ascani, Luca Arcaini, Giorgio Inghirami, Marco Paulli, Brunangelo Falini   +14 more
doaj   +1 more source

No genetic evidence for involvement of Deltaretroviruses in adult patients with precursor and mature T-cell neoplasms [PDF]

, 2007
Background The Deltaretrovirus genus comprises viruses that infect humans (HTLV), various simian species (STLV) and cattle (BLV). HTLV-I is the main causative agent in adult T-cell leukemia in endemic areas and some of the simian T-cell lymphotropic ...
Burmeister, Thomas, Hoelzer, Dieter (Prof. Dr.), Hummel, Michael, Schwartz, Stefan, Thiel, Eckhard   +4 more
core   +2 more sources